乳腺癌患者术后皮瓣坏死发生情况及其高危因素  

Incidence and Risk Factors of Flap Necrosis in Patients with Breast Cancer After Operation

作　　者：冯静影 李文涛 韩智培 胡瑾瑾 FENG Jingying;LI Wentao;HAN Zhipei;HU Jinjin(Breast Surgery Department,Henan Provincial People’s Hospital Breast Hospital,People’s Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]河南省人民医院乳腺病医院,郑州大学人民医院乳腺外科,河南郑州450000

出　　处：《河南医学研究》2022年第21期3882-3884,共3页Henan Medical Research

摘　　要：目的观察乳腺癌患者术后皮瓣坏死的发生情况,并探究其影响因素。方法选取2019年10月至2021年10月河南省人民医院收治的150例接受乳腺癌根治术的患者作为研究对象,术后随访14 d,记录患者术后皮瓣坏死发生情况。收集患者的一般资料,经logistic回归分析乳腺癌患者术后发生皮瓣坏死的危险因素。结果随访14 d,150例乳腺癌术后患者中41例(27.33%)发生皮瓣坏死。发生组患者乳腺癌位置、体质量指数(BMI)、切口类型、合并2型糖尿病(T2DM)与未发生组患者比较,差异有统计学意义(P<0.05)。两组间其他基线资料比较,差异无统计学意义(P>0.05)。经logistic回归分析,结果显示,外侧区肿瘤、BMI过高、斜向切口、合并T2DM是乳腺癌患者术后发生皮瓣坏死的危险因素(OR>1,P<0.05)。结论外侧区肿瘤、BMI过高、斜向切口、合并T2DM为乳腺癌患者术后发生皮瓣坏死的危险因素。Objective To observe the occurrence of postoperative flap necrosis in patients with breast cancer and explore its influencing factors.Methods A total of 150 patients who underwent radical mastectomy for breast cancer from October 2019 to October 2021 in Henan People’s Hospital were selected as the study subjects.The patients were followed up for 14 days,and the incidence of postoperative flap necrosis was recorded.The general data of patients were collected,and the risk factors of skin flap necrosis in breast cancer patients were analyzed by logistic regression.Results After 14 days of follow-up,41cases(27.33%)of 150 patients with breast cancer underwent flap necrosis.The location of breast cancer,body mass index(BMI),incision type and type 2 diabetes mellitus(T2DM)of the patients in the occurrence group were statistically different from those in the non occurrence group(P<0.05).There was no statistical difference in other baseline data between the two groups(P>0.05).By logistic regression analysis,the results showed that tumor in lateral region,high BMI,oblique incision and T2DM were the risk factors of skin flap necrosis in patients with breast cancer after operation(OR>1,P<0.05).Conclusion Lateral region tumor,high BMI,oblique incision and T2DM are the risk factors of skin flap necrosis in patients with breast cancer after operation.

关 键 词：乳腺癌 乳腺癌根治术 皮瓣坏死 皮肤张力 2型糖尿病 

分 类 号：R737.9[医药卫生—肿瘤]