DCE-MRI联合超声在乳腺癌临床诊断中的应用与分析  

Application and Analysis of DCE-MRI Combined with Ultrasound in the Clinical Diagnosis of Breast Cancer

作　　者：陈雨娜[1] 吴云虎 周玫娟[1] 董建党[3] CHEN Yuna;WU Yunhu;ZHOU Meijuan;DONG Jiandang(College of Medical Technology,Shangqiu Medical College,Shangqiu 476000,Henan,P.R.China;Department of Medical Technology,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,Henan,P.R.China;Department of Ultrasound,The First People’s Hospital of Shangqiu,Shangqiu 476000,Henan,P.R.China)

机构地区：[1]商丘医学高等专科学校医学技术学院,河南商丘476000 [2]河南中医药大学附属第一医院医技科,河南郑州450000 [3]商丘市第一人民医院超声科,河南商丘476000

出　　处：《影像科学与光化学》2022年第6期1417-1422,共6页Imaging Science and Photochemistry

摘　　要：本文探讨动态增强MR扫描(DCE-MRI)联合超声在乳腺癌临床诊断中的应用价值。回顾性分析100例乳腺肿瘤患者相关资料,所有患者均接受超声、DCE-MRI检查,分析良恶性肿瘤DCE-MRI特征差异,比较两种检查方式下乳腺影像报告及数据系统(BI-RADS)分级评估乳腺良恶性肿瘤的价值,分析两者联合的诊断价值。DCE-MRI检查显示,良性及恶性肿瘤形状、边缘、内部强化特征、TIC曲线等征象比较,差异具有统计学意义(P<0.05);恶性肿瘤容量转移常数(Ktrans)、速率常数(Kep)高于良性肿瘤,血管外细胞间隙容积分数(Ve)低于良性肿瘤(P<0.05);超声诊断乳腺良恶性肿瘤的敏感度、特异度、准确度分别为94.12%、83.67%、89.00%,DCE-MRI的敏感度、特异度、准确度分别为98.04%、89.79%、94.00%,两者联合的敏感度、特异度、准确度分别为100.00%、97.95%、99.00%,联合诊断准确度高于超声诊断(P<0.05)。DCE-MRI及乳腺超声对乳腺病灶性质具有较好的诊断价值,两者联用可为患者病情诊断提供更多参考依据。This study investigated the application value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with ultrasound in clinical diagnosis of breast cancer.The relevant data of 100 patients with breast tumors were retrospectively analyzed.All of the patients completed ultrasound and DCE-MRI examinations.The DCE-MRI characteristics of benign and malignant tumors were comparatively analyzed.The value of the Breast Imaging Reporting and Data System(BI-RADS)in evaluating benign and malignant breast tumors under the two examination methods was analyzed.The diagnostic value of the combination of the two was analyzed.DCE-MRI showed that the shapes,edges,internal enhancement features,and TIC curves of benign and malignant tumors were significantly different.The volume transfer constant(Ktrans)and rate constant(Kep)of malignant tumors were higher than those of benign tumors,and extracellular space volume percentage(Ve)was lower than that of benign tumors.The sensitivity,specificity and accuracy of ultrasound to diagnose benign and malignant breast tumors were 94.12%,83.67%and 89.00%.The sensitivity,specificity and accuracy of DCE-MRI were 98.04%,89.79%and 94.00%.The sensitivity,specificity and accuracy of combined diagnosis with the two were 100.00%,97.95%and 99.00%.The accuracy of combined diagnosis was higher than that of ultrasonic diagnosis(P<0.05).The above results indicate that both DCE-MRI and breast ultrasound are helpful in nature diagnosis of breast lesions,and combined use of the two can provide more reference for the diagnosis.

关 键 词：乳腺癌 超声 磁共振成像 动态增强MR扫描 乳腺影像报告及数据系统 

分 类 号：R737.9[医药卫生—肿瘤]