脑水肿无创动态监测仪在自发性脑出血中的应用  

Application of non-invasive dynamic monitoring of cerebral edema in spontaneous cerebral hemorrhage

作　　者：高文文 蒋小兵 陈鹏[1] 王凤鹿 杨磊[1] 袁致海[1] 张亮 曹喜茹 李小强[1] 赵海康[1] GAO Wen-wen;JIANG Xiao-bing;CHEN Pen;WANG Feng-lu;YANG Lei;YUAN Zhi-hai;ZHANG Liang;CAO Xi-ru;LI Xiao qiang;ZHAO Hai-kang(Department of Neurosurgery,The Second Affiliated Hospital of Xi'an Medical University,Xi'an 730038,China)

机构地区：[1]西安医学院第二附属医院神经外科,西安710038

出　　处：《中国临床神经外科杂志》2022年第10期822-824,共3页Chinese Journal of Clinical Neurosurgery

基　　金：陕西省重点研发计划项目(2020ZDLSF01-02);西安医学院第二附属医院青年项目(22ky0115)。

摘　　要：目的探讨脑水肿无创动态监测仪在自发性脑出血中的应用价值。方法2020年1月至2021年1月前瞻性收集自发性脑出血20例,均行开颅血肿清除术治疗。入院后均行脑室内颅内压(ICP)动态监测2周,采用BORNBE脑水肿无创动态监护仪监测扰动系数(DC)评估脑水肿。结果发病1周内,DC、ICP、GCS评分均无明显变化(P>0.05);发病2周,DC和ICP明显降低(P<0.05),GCS评分明显增高(P<0.05)。DC最低值与ICP呈明显负相关(r=-0.41,P<0.01),与GCS评分呈明显正相关(r=0.54,P<0.01),与发病6个月GOS评分呈明显正相关(r=0.52,P<0.01)。结论对自发性脑出血,脑水肿无创动态监护仪可连续、动态监测脑水肿情况,具有评估病人ICP的作用;而且,与脑室内ICP监测相比,具有无创、操作简单、可重复性好、动态观察的优势。Objective To evaluate the application value of non-invasive dynamic monitoring of cerebral edema in the patients with spontaneous cerebral hemorrhage(SCH).Methods A total of 20 patients with SCH were prospectively recruited from January 2020 to January 2021.All patients underwent craniotomy and hematoma removal.Intraventricular intracranial pressure(ICP)was dynamically monitored and the disturbance coefficient(DC)was monitored by BORNE non-invasive dynamic monitor to evaluate the cerebral edema for 2 weeks after onset.Results There were no significant changes in DC,ICP and GCS scores within 1 week after onset(P>0.05).Two weeks after onset,DC and ICP were significantly decreased(P<0.05),and GCS score was significantly increased(P<0.05).The lowest value of DC was significantly negatively correlated with ICP(r=-0.41,P<0.01),significantly positively correlated with GCS score(r=0.54,P<0.01),and significantly positively correlated with GOS score at 6 months after onset(r=0.52,P<0.01).Conclusions The non invasive dynamic monitoring of cerebral edema can continuously and dynamically monitor cerebral edema to evaluate ICP in the patients with SCH.Compared with intraventricular ICP monitoring,it has the advantages of non-invasive,simple operation,good repeatability and dynamic observation.

关 键 词：自发性脑出血 脑水肿无创动态监护仪 临床应用 

分 类 号：R743.34[医药卫生—神经病学与精神病学]