肠道产甲烷菌与肠道疾病的关系研究进展  

Research progress on the relationship between intestinal methanogens and intestinal diseases

作　　者：易鑫 肖嫩群[1] 谭周进[1] YI Xin;XIAO Nen-qun;TAN Zhou-jin(Hunan University of Chinese Medicine,Changsha 410208,China)

机构地区：[1]湖南中医药大学,湖南长沙410208

出　　处：《中国感染控制杂志》2022年第11期1151-1156,共6页Chinese Journal of Infection Control

基　　金：湖南省自然科学基金(2020JJ4468)。

摘　　要：肠道产甲烷菌是一类将氢气和二氧化碳生成甲烷的厌氧菌,研究证实其与人体肠道疾病密切相关,因此深入探索肠道产甲烷菌在肠道疾病中的作用机制具有重要意义。本文就肠道产甲烷菌的特点、种类、定植特征,及其与肥胖、肠易激综合征、炎症性肠病、结直肠癌、憩室病等疾病之间的关系进行综述,着重梳理肠道产甲烷菌在这些疾病中可能发生的机制,为人体肠道疾病的预防、诊断和治疗提供一定的新思路。Intestinal methanogens are anaerobic bacteria that produce methane from hydrogen and carbon dioxide,studies have confirmed that they are closely related to human intestinal diseases,therefore,it is of great significance to explore the mechanism of intestinal methanogens in intestinal diseases.This paper reviews the characteristics,types and colonization characteristics of intestinal methanogens as well as their relationship with obesity,irritable bowel syndrome,inflammatory bowel disease,colorectal cancer,diverticulosis and other diseases,focusing on the possible mechanism of intestinal methanogens in these diseases,so as to provide new ideas for the prevention,diagnosis and treatment of human intestinal diseases.

关 键 词：产甲烷菌 甲烷 肠道疾病 厌氧菌 肠道菌群 肠道特征菌 

分 类 号：R574[医药卫生—消化系统]