角膜后弹力层脱离研究现状  

Current Status of Descemet’s Membrane Detachment

作　　者：曾琴琴[1] 付书华[1] 陆莹[1] ZENG Qin-qin;FU Shu-hua;LU Ying(Center of Ophthalmology,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第二附属医院眼科中心,南昌330006

出　　处：《实用临床医学（江西）》2022年第5期125-129,共5页Practical Clinical Medicine

摘　　要：角膜后弹力层是角膜内皮层的基底膜,在维持角膜完整性和透明性方面起重要作用。角膜后弹力层脱离(DMD)的解剖因素同角膜后弹力层与基质层之间黏附疏松有关,两层间易受各种因素作用而至二者分离,房水进入角膜基质内,引起持续性角膜水肿。DMD是眼内手术及眼外伤等的严重并发症之一,若不能及时发现及处理,角膜内皮功能失代偿致严重角膜水肿,导致视力明显下降。临床处理DMD需考虑其脱离的位置、范围、原因以及不同脱离类型。文章综述DMD的可能发生机制、临床表现、诊断及处理方法等的研究进展。Descemet’s membrane is the basement membrane of the endothelial layer and plays an important role in maintaining corneal integrity and clarity.The anatomic factor of Descemet’s membrane detachment(DMD)is related to the loose adhesion between Descemet’s membrane and stroma.The two layers can be easily separated by various factors.Aqueous humor enters the corneal stroma,causing persistent corneal edema.DMD is one of the most serious complications of intraocular surgery and ocular trauma.If it cannot be detected and treated in time,the corneal endothelial dysfunction causes severe corneal edema,and leads to a decrease in visual acuity.The location,scope,causes and types of DMD should be considered in clinical treatment.This article reviews the research progress in possible mechanisms,clinical manifestations,diagnosis and treatment of DMD.

关 键 词：角膜后弹力层脱离 白内障超声乳化切除术 小梁切除术 穿透性角膜移植术 

分 类 号：R772.2[医药卫生—眼科]