经阴道彩色多普勒超声联合血清CA125鉴别诊断卵巢肿瘤良恶性效能  

Efficacy of transvaginal color Doppler ultrasound combined with serum cancer antigen 125 level for differential diagnosing benign or malignant ovarian tumors

作　　者：顾涛[1] 俞佳丽 鲁勇 范毅 吴晓容[1] GU Tao;YU Jiali;LU Yong;FAN Yi;WU Xiaorong(Rong County People's Hospital of Sichuan Province,Sichuan Province,643100)

机构地区：[1]四川省荣县人民医院,643100

出　　处：《中国计划生育学杂志》2022年第11期2620-2623,共4页Chinese Journal of Family Planning

摘　　要：目的:分析经阴道彩色多普勒超声测定收缩期峰值血流速度(PSV)、阻力指数(RI)联合血清癌抗原125(CA125)检测在卵巢肿瘤良恶性中的鉴别诊断价值。方法:回顾性收集2017年12月-2021年12月本院接受治疗的91例卵巢肿瘤患者临床资料,根据手术病理结果分为良性组(n=56)和恶性组(n=35),比较两组PSV、RI、CA125,受术者工作特征曲线(ROC)分析良恶性诊断价值。结果:恶性组PSV、CA125大于良性组,RI小于良性组(均P<0.05)。ROC曲线分析显示,鉴别诊断卵巢肿瘤良恶性RI诊断特异度(88.2%)最高,PSV、RI、CA125联合检测鉴别卵巢肿瘤良恶性的灵敏度(83.0%)、准确度(84.6%)、阴性预测值(91.1%)均高于单一检测。结论:PSV、RI、CA125在良恶性卵巢肿瘤患者中存在差异,联合检测可提高卵巢肿瘤良恶性的鉴别灵敏度和准确度,为后续治疗方案制定提供参考。Objective:To analyze the values of peak systolic blood flow velocity(PSV)and resistance index(RI)measured by transvaginal color Doppler ultrasound combined with serum cancer antigen 125(CA125)level for differential diagnosing benign or malignant ovarian tumors.Methods:A total of 91 patients with ovarian tumors from December 2017 to December 2021 were collected retrospectively.These patients were divided into group A(56 patients with benign ovarian tumors)and group B(35 patients with malignant ovarian tumors)according to their pathological results after surgery.The values of PSV and RI,and the CA125 level of the patients were compared between the two groups.The diagnostic value of the values of PSV and RI,and the CA125 level of the patients for their benign or malignant ovarian tumors was analyzed by receiver operating characteristic(ROC)curve.Results:The PSV value and the CA125 level of the patients in group B were significantly higher than those of the patients in group A,and the RI value of the patients in group B was significantly lower(all P<0.05).ROC curve analysis showed that the specificity of the RI value for differential diagnosing benign or malignant ovarian tumors was the highest(88.2%).The sensitivity(83.0%),the accuracy(84.6%),and the negative predictive value(91.1%)of the PSV and RI values combined with the CA125 level of the patients for differential diagnosing their benign or malignant ovarian tumors were significantly higher than those of the PSV value,the RI value,or the CA125 level alone.Conclusion:The PSV value,the RI value,and the CA125 level of the patients with benign or malignant ovarian tumors are different.The PSV and RI values combined with the CA125 level of the patients for differential diagnosing their benign or malignant ovarian can improve the sensitivity and the accuracy of diagnosis,which is conducive to the development of subsequent treatment plan.

关 键 词：卵巢肿瘤 良恶性 彩色多普勒超声 血清癌抗原125 鉴别诊断 

分 类 号：R737.31[医药卫生—肿瘤] R445.1[医药卫生—临床医学]