铒激光治疗中重度牙周炎的效果及对骨钙素水平的影响  

Effect of Erbium laser on moderate and severe periodontitis and its influence on osteocalcin level

作　　者：李雁[1] LI Yan(Department of Stomatology,Dalian Friendship Hospital,Liaoning Province,Dalian 116001,China)

机构地区：[1]大连市友谊医院口腔科,辽宁大连116001

出　　处：《中国当代医药》2022年第32期138-141,共4页China Modern Medicine

摘　　要：目的探讨铒激光治疗中重度牙周炎的效果及对骨钙素水平的影响。方法选取2017年1月至2020年12月大连市友谊医院口腔科收治的112例中重度牙周炎患者作为研究对象,按照随机数字表法分为对照组(56例)与试验组(56例),对照组采用常规治疗方法,试验组采用铒激光治疗方法。比较两组患者的临床治疗效果,治疗后1、3、6个月的龈沟液中骨钙素水平,以及治疗前后的血清指标[肿瘤坏死因子-α(TNF-α)、血清白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)与C反应蛋白(CRP)]水平。结果试验组的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后1、3、6个月,试验组患者龈沟液中的骨钙素水平均低于对照组,差异有统计学意义(P<0.05)。两组患者治疗后的TNF-α、IL-1β、IL-6及CRP水平均低于本组治疗前,差异有统计学意义(P<0.05);试验组患者治疗后的TNF-α、IL-1β、IL-6及CRP水平均低于对照组,差异有统计学意义(P<0.05)。结论对中重度牙周炎患者实施铒激光治疗不仅能达到良好的临床治疗效果,还能改善各个时点骨钙素水平,改善治疗后血清指标水平,具有较好的推广价值。Objective To investigate the effect of Erbium laser in the treatment of moderate to severe periodontitis and its influence on the level of osteocalcin.Methods A total of 112 patients with moderate to severe periodontitis admitted to the Department of Stomatology,Dalian Friendship Hospital from January 2017 to December 2020 were selected as the research subjects,and they were divided into control group(56 cases)and experimental group(56 cases)according to the random number table method.The control group was treated with conventional treatment methods,while the experimental group was treated with Erbium laser.The clinical outcomes,osteocalcin levels in the gingival sulcus fluid at 1,3,and 6 months after treatment,and serum indexes(tumor necrosis factor-α[TNF-α],serum interleukin-1β[IL-1β],interleukin-6[IL-6]and C-reactive protein[CRP])level before and after treatment were compared between the two groups.Results The total effective rate of treatment in the experimental group was higher than that in the control group,with statistically significant difference(P<0.05).At 1,3,and 6 months after treatment,the levels of osteocalcin in the gingival sulcus fluid of the patients in the experimental group were lower than those in the control group,with statistically significant differences(P<0.05).The levels of TNF-α,IL-1β,IL-6,CRP after treatment in two groups were lower than those before treatment,with statistically significant differences(P<0.05).After treatment,the levels of TNF-α,IL-1β,IL-6,CRP in experimental group were lower than those in the control group,with statistically significant differences(P<0.05).Conclusion The Erbium laser treatment of patients with moderate to severe periodontitis can not only achieve good clinical treatment effects,but also improve the level of osteocalcin at each point in time can improve the serum index level after treatment,which has promotion value.

关 键 词：重度牙周炎 铒激光 效果 骨钙素水平 影响 

分 类 号：R781.4[医药卫生—口腔医学]