Genome-wide analyses of nonsyndromic cleft lip with or without palate identify 20 new risk loci in the Chinese Han population  

作　　者：Bao Li Liang Yong Yafen Yu Yanqin Yu Qi Zhen Huiyao Ge Yiwen Mao Weiwei Chen Yanxia Yu Yirui Wang Zhuo Li Wencheng Fan Chang Zhang Xia Hu Ruixue Zhang Lu Cao Hao Liu Zhuan Bian Miao He Liangdan Sun 

机构地区：[1]Department of Dermatology,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230022,China [2]Institute of Dermatology,Anhui Medical University,Hefei,China [3]Key Laboratory of Dermatology,Ministry of Education,Anhui Medical University,Hefei,Anhui 230022,China [4]Inflammation and Immune Mediated Diseases Laboratory of Anhui Province,Hefei,Anhui 230022,China [5]Anhui Provincial Institute of Translational Medicine,Hefei,Anhui 230022,China [6]The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)and Key Laboratory of Oral Biomedicine Ministry of Education,School and Hospital of Stomatology,Wuhan University,Wuhan,Hubei 430079,China

出　　处：《Journal of Genetics and Genomics》2022年第9期903-905,共3页遗传学报（英文版）

基　　金：funded by the National Natural Science Foundation of China(81970904 to MH,81970923 to ZB);Anhui Institute of Translational Medicine(ZHYX2020A005 to LS);the University Synergy Innovation Program of Anhui Province(GXXT-2020-064 to LS);Clinical medicine discipline construction project of Anhui Medical University(2021lcxk008 to LS);the National Key Research and Development Program(2016YFC1000505 to ZB)。

摘　　要：Orofacial clefts(OFCs),particularly cleft lip with or without cleft palate(CL/P)and cleft palate only(CPO),are among the most common birth defects in humans(Mossey et al.,2009;Dixon et al.,2011).The birth prevalence rate of OFCs in China is reported to be as high as 1.66 per thousand newborns.

关 键 词：al. PALATE DIXON 

分 类 号：R782.2[医药卫生—口腔医学]