基于计算机体层摄影血管造影分析基底动脉瘤破裂的影响因素  

Analysis on the influencing factors of basilar aneurysm rupture based on computed tomography angiography

作　　者：杨柳 张斯佳 王东东 Yang Liu;Zhang Sijia;Wang Dongdong(Department of Imaging,The Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine(Zhengzhou People′s Hospital),Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第五临床医学院(郑州人民医院)影像科,郑州450000

出　　处：《中国临床实用医学》2022年第4期21-24,共4页China Clinical Practical Medicine

基　　金：河南省医学科技攻关计划项目(LHGJ20210708)。

摘　　要：目的基于计算机体层摄影血管造影(CTA)分析基底动脉瘤破裂的影响因素。方法本研究为回顾性研究,选取2020年6月至2021年4月河南中医药大学第五临床医学院(郑州人民医院)影像科检查的196例基底动脉瘤患者,收集患者的临床资料,男101例,女95例,年龄(61.75±8.26)岁,年龄范围为40~79岁。所有患者均通过CTA检测,通过logistic回归分析动脉瘤形态学参数[破裂与未破裂动脉瘤位置以及瘤颈、载瘤动脉直径(Dv)、流入角(θF)、流出角(θP)、破裂动脉瘤大小、瘤体深度与瘤颈宽度的比值(AR)、瘤体深度与载瘤动脉直径的比值(SR)、面积比]与基底动脉瘤破裂的关系。结果196例患者瘤体破裂127例,未破裂瘤体69例。破裂与未破裂动脉瘤位置以及瘤颈、Dv、θF、θP水平比较,差异无统计学意义(P>0.05);破裂动脉瘤大小[(5.52±1.01)mm]、AR(1.90±0.58)、SR(2.26±0.65)、面积比(1.40±0.41)均大于未破裂动脉瘤[(4.17±1.14)mm、(1.28±0.37)、(1.51±0.39)、(1.22±0.35)],差异有统计学意义(P<0.05)。logistic多元线性回归分析结果显示动脉瘤大小以及AR、SR、面积比增加均是影响基底动脉瘤破裂的独立危险因素,差异有统计学意义(P<0.05)。结论CTA测量参数中动脉瘤直径大、面积比值高、AR值高与SR值高是动脉瘤破裂的独立危险因素。Objective To analyze the influencing factors of basilar aneurysm rupture based on computed tomography angiography(CTA).Methods This study was a retrospective study,a total of 196 patients with basilar aneurysms admitted to department of Imaging in The Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine(Zhengzhou People′s Hospital)were enrolled between June 2020 and April 2021.The clinical data of patients were collected,there were 101 males and 95 females,with the age was(61.75±8.26)years old,ranging from 40 to 79 years old.All patients underwent CTA.The relationship between morphological parameters of aneurysms[sites and aneurysm neck of ruptured and unruptured aneurysms,parent vessel average diameter(Dv),flow angle(θF),parent-daughter angle(θP),size of ruptured aneurysms,Tumor body depth and tumor neck width aspect ratio(AR),aneurysm depth to parent artery diameter size ratio(SR),area ratio]and basilar aneurysm rupture was analyzed by logistic regression analysis.Results Of the 196 patients,there were 127 cases with aneurysm rupture and 69 cases without rupture.The difference in sites,aneurysm neck,Dv,θF andθP between ruptured and unruptured aneurysms was not statistically significant(P>0.05).The size[(5.52±1.01)mm],AR(1.90±0.58),SR(2.26±0.65)and area ratio(1.40±0.41)in ruptured aneurysms were all higher than those in unruptured aneurysms[(4.17±1.14)mm,(1.28±0.37),(1.51±0.39),(1.22±0.35)],and the differences were statistically significant(P<0.05).The results of logistic multivariate linear regression analysis showed that increased aneurysm size,AR,SR and area ratio were independent risk factors of basilar aneurysm rupture,and the differences were statistically significant(P<0.05).Conclusions In the parameters measured by CTA,long aneurysm diameter,high area ratio,high AR and high SR were independent risk factors of aneurysm rupture.

关 键 词：基底动脉瘤 计算机断层扫描血管造影 形态学参数 载瘤动脉直径 

分 类 号：R743[医药卫生—神经病学与精神病学]