颈动脉狭窄侧支循环代偿与缺血性脑血管病的相关性  

Correlation Between Collateral Circulation Compensation of Carotid Stenosis and Ischemic Cerebrovascular Disease

作　　者：李丹 佟岩 LI Dan;TONG Yan(Department of Electrodiagnosis,FAW General Hospital,Changchun Jilin 130000,China)

机构地区：[1]吉林省一汽总医院电诊科,吉林长春130000

出　　处：《中国卫生标准管理》2022年第20期99-102,共4页China Health Standard Management

摘　　要：目的 分析重度颈动脉狭窄颅内侧支循环代偿状态与缺血性脑血管病的相关性。方法 本次研究使用抽样调查的方法选取研究对象,将抽样时间设定在2021年2月—2022年2月,共抽选吉林省一汽总医院收治的重度颈动脉狭窄患者80例,所选患者均经临床诊断为重度颈动脉狭窄。抽样完毕后将所有患者随机分为两组,一组是症状组(有缺血性脑血管疾病患者41例),一组是无症状组(无缺血性脑血管疾病患者39例)。对两组患者进行经颅多普勒超声(transcranial Doppler ultrasound,TCD)检查,对比两组患者的单侧颈动脉狭窄程度、侧支血管代偿情况、Willis环完整及变异情况。结果 经比较,症状组患者的单侧颈动脉狭窄严重程度高于无症状组;症状组患者的Ⅱ级代偿例数多于无症状组;与无症状组患者相比,症状组患者的前后环变异率高,前后环完整率低;无症状患者侧支血管情况优于症状组,组间数据差异有统计学意义(P <0.05)。结论 重度颈动脉狭窄患者是否出现缺血性脑血管病与患者的单侧颈动脉狭窄程度、侧支血管代偿情况、Willis环完整及变异情况有关。Objective To analyze the relationship between the compensatory state of the intracranial collateral circulation and ischemic cerebrovascular disease in patients with severe carotid artery stenosis carotid artery stenosis.Methods In this study,the subjects were selected by sampling survey.The sampling time was set from February 2021 to February 2022.A total of 80 patients with severe carotid artery stenosis were selected from FAW General Hospital.All the selected patients were clinically diagnosed as severe carotid artery stenosis.After sampling,all patients were randomly divided into two groups,one group was the symptom group(41 patients with ischemic cerebrovascular disease) and the other group was the asymptomatic group(39 patients without ischemic cerebrovascular disease).Transcranial Doppler ultrasound(TCD) examination was performed in the two groups.The degree of unilateral carotid artery stenosis,collateral vessel compensation,integrity and variation of Willis ring were compared between the two groups.Results Compared with the asymptomatic group,patients in the symptomatic group had higher severity of unilateral carotid artery stenosis;patients in the symptomatic group had more class Ⅱ compensations than those in the asymptomatic group;and patients in the symptomatic group had a higher rate of anterior and posterior loop variability than those in the asymptomatic group,the intact rate of anterior and posterior annulus was low,the condition of collateral vessels in asymptomatic patients was better than that in symptomatic group,and the differences were statistically significant(P < 0.05).Conclusion The presence of ischemic cerebrovascular disease in patients with severe carotid artery stenosis is associated with unilateral carotid artery stenosis,collateral vessel compensation,and integrity and variability of the circle of Willis.

关 键 词：重度颈动脉狭窄 颅内侧支循环 缺血性脑血管病 WILLIS环 侧支血管代偿 相关性研究 

分 类 号：R743[医药卫生—神经病学与精神病学]