羟丁酸钠改善睡眠障碍作用的临床研究进展  

Clinical research progress of sodium oxybate in improving sleep disorders

作　　者：赵安琪 赵平[1] Zhao Anqi;Zhao Ping(Department of Anesthesiology,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院麻醉科,辽宁沈阳110004

出　　处：《实用药物与临床》2022年第11期1032-1036,共5页Practical Pharmacy and Clinical Remedies

摘　　要：羟丁酸钠曾广泛用于临床镇静和麻醉,后因其麻醉作用单一而逐渐减少使用。近年来,羟丁酸钠被证实可以治疗发作性睡病,同时对改善阿尔茨海默病和帕金森病等疾病的睡眠障碍症状有效。本文对羟丁酸钠改善睡眠障碍作用的临床应用现况及相关研究进展进行综述,并探讨了其潜在的临床应用价值。Sodium oxybate has been widely used in clinical sedation and anesthesia, but it has been gradually reduced because of its single anesthetic effect.In recent years, sodium oxybate has been proved to be effective in the treatment of narcolepsy and sleep disorders related to Alzheimer′s disease and Parkinson′s disease.This paper reviews the current clinical application and related research progress of sodium oxybate in improving sleep disorders, and explores its potential clinical application value.

关 键 词：羟丁酸钠 睡眠障碍 阿尔茨海默病 帕金森病 

分 类 号：R740[医药卫生—神经病学与精神病学]