双眼经上皮准分子激光角膜切削术后圆锥角膜1例  

Keratoconus after transepithelial photorefractive keratectomy:a case report

作　　者：闫春晓 亓晓琳 王妙霖 张立军 Yan Chunxiao;Qi Xiaolin;Wang Miaolin;Zhang Lijun(Dalian Eye Hospital,The Third People′s Hospital of Dalian affiliated to Dalian Medical University,Dalian 116033,China;Eye Institute of Shandong First Medical University,Eye Hospital of Shandong First Medical University(Shandong Eye Hospital),State Key Laboratory Cultivation Base,Shandong Provincial Key Laboratory of Ophthalmology,School of Ophthalmology,Shandong First Medical University,Jinan 250021,China)

机构地区：[1]大连医科大学附属大连市第三人民医院大连市眼科医院,大连116033 [2]山东第一医科大学附属眼科研究所山东第一医科大学附属眼科医院(山东省眼科医院)山东省眼科学重点实验室‑省部共建国家重点实验室培育基地山东第一医科大学眼科学院,济南250021

出　　处：《中华眼科杂志》2022年第10期809-814,共6页Chinese Journal of Ophthalmology

基　　金：辽宁省自然科学基金指导计划(20180550976);辽宁省自然基金资助计划(2020‑MS‑339);大连市科技创新基金项目(2019J13SN105);大连市医学科学研究计划项目(1911032)。

摘　　要：1例24岁双眼夜间视力下降2年男性患者,5年前行经上皮准分子激光角膜切削术(TransPRK)治疗双眼近视眼,过敏性结膜炎病史3年,临床经检查诊断为双眼圆锥角膜。行双眼经上皮角膜胶原交联术,术后随访6个月,活体共聚焦显微镜检查显示核黄素与纤维氨基交联成功,圆锥角膜无进展。针对角膜屈光手术候选患者群体,临床应高度重视圆锥角膜的早期全面筛查,以提高角膜屈光手术的长期安全性。A 24‑year‑old male was treated with transepithelial photorefractive keratectomy for myopia in both eyes 5 years ago.He had allergic conjunctivitis for 3 years.The night vision of both eyes was decreased for 2 years.The clinical diagnosis was keratoconus binoculus.Therefore,corneal collagen cross‑linking was performed in both eyes,and the follow‑up was 6 months.Confocal microscopy showed that the cross‑linking of riboflavin and fiber amino was successful,and the keratoconus did not progress during the follow‑up.Although there have been few case reports of keratoconus after transepithelial photorefractive keratectomy at home and abroad,great importance should be attached to the early and comprehensive screening of keratoconus in the candidates of refractive surgery in order to improve the long‑term safety.

关 键 词：圆锥角膜 屈光性角膜切削术 激光 准分子 胶原 交联试剂 上皮 角膜 显微镜检查 共焦 

分 类 号：R779.6[医药卫生—眼科]