双相障碍混合状态伴强迫症状诊断与治疗1例  

Diagnosis and treatment of mixed bipolar states with obsessive-compulsive symptoms:a case report

作　　者：徐劲节 王威[1] XU Jinjie;WANG Wei(Beijing Anding Hospital Affiliated to Capital Medical University,Beijing 100088,China)

机构地区：[1]首都医科大学附属北京安定医院,国家精神疾病医学中心,国家精神心理疾病临床医学研究中心,精神疾病诊断与治疗北京市重点实验室,北京100088

出　　处：《中国神经精神疾病杂志》2022年第9期554-556,共3页Chinese Journal of Nervous and Mental Diseases

基　　金：北京市属医院科研培育计划项目(编号:PX2021070);北京安定医院院科研基金(编号:YJ2022-06)。

摘　　要：双相障碍混合状态伴强迫症状的诊断与治疗一直面临挑战,本文回顾性分析1例患者的临床资料并进行文献复习,旨在促进精神科医生对本病识别与治疗的认识。患者为32岁男性,诊断“双相障碍,目前为混合状态”,伴强迫症状,给予碳酸锂、丙戊酸盐联合喹硫平治疗效果不佳,将喹硫平换为齐拉西酮后情绪渐稳定,强迫症状减轻,疗效确切。The diagnosis and treatment of mixed bipolar states with obsessive-compulsive symptoms have been challenging.In this paper,we retrospectively analyzed the clinical data of one patient and conducted a literature review to facilitate the recognition and treatment of this disorder.A 32-year-old male patient was admitted to the hospital and diagnosed with mixed bipolar states with obsessive-compulsive symptoms.Lithium and valproate combined with quetiapine were ineffective,and the replacement of quetiapine with ziprasidone resulted in gradual stabilization of mood and reduced obsessive-compulsive symptoms.This case report is intended to provide a reference and experience for clinical work.

关 键 词：双相障碍 混合状态 强迫症状 齐拉西酮 心境稳定剂 抗精神病药 抗抑郁药 

分 类 号：R749.4[医药卫生—神经病学与精神病学]