双耳分听范式在精神分裂症听觉语言信息处理中的研究现状  

Research status of dichotic listening paradigm in auditory and linguistic information processing in schizo⁃phrenia

作　　者：翟小林 程龙[2] 赵文涛 韩柏 ZHAI Xiaolin;CHENG Long;ZHAO Wentao;HAN Bai(Department of Mental Health,the First Clinical Medical College of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一临床医学院精神病与精神卫生学教研室,太原030001 [2]山西医科大学第一临床医学院精神卫生科 [3]北京市西城区平安医院精神科

出　　处：《中国神经精神疾病杂志》2022年第9期568-571,共4页Chinese Journal of Nervous and Mental Diseases

摘　　要：双耳分听(dichotic-listening,DL)范式作为一种非侵入性的研究手段,在精神分裂症(schizophrenia,SZ)患者听觉语言信息处理的研究中有重要作用。本综述回顾了DL范式在SZ患者听觉语言信息处理中的研究进展,包括DL范式在SZ患者大脑偏侧化、听觉感觉门控方面的研究,及其在SZ患者幻听相关研究中的应用。目前研究提示SZ患者听觉信息处理中的异常与偏侧化降低、听觉感觉门控功能障碍有关,在DL范式中表现为右耳优势下降,这种听觉信息处理异常与患者的幻听症状相关。Dichotic-listening(DL)paradigm,as a non-invasive method,plays an important role in the study of auditory language information processing in schizophrenia(SZ)patients.This paper reviews the research progress of DL paradigm in auditory language information processing in SZ patients,including the research of DL paradigm in brain lateralization and auditory sensory gating in SZ patients,and its application in auditory auditory hallucinations in SZ patients.Current studies suggest that auditory information processing abnormalities in SZ patients are related to decreased lateralization and auditory sensory gating dysfunction,which is manifested as decreased right ear dominance in DL paradigm,and this auditory information processing abnormality is related to auditory hallucination symptoms of patients.

关 键 词：精神分裂症 双耳分听 功能偏侧化 感觉门控 幻听 磁共振成像 神经电生理 

分 类 号：R749.3[医药卫生—神经病学与精神病学]