自体牙本质颗粒与Bio-Oss骨粉植入引导骨再生治疗牙周骨缺损效果比较  

Comparative analysis of the effect of autologous dentin particles and implantation of Bio-Oss on guided bone regeneration in the treatment of periodontal bone defects

作　　者：毛新霞 林晓炜 魏轩 李琴 MAO Xin-xia;LIN Xiao-wei;WEI Xuan;LI Qin(Department of Stomatology,Zhangye People's Hospital Affiliated to Hexi University,Zhangye 734000,Gansu Province,China)

机构地区：[1]河西学院附属张掖人民医院口腔科,甘肃张掖734000

出　　处：《上海口腔医学》2022年第5期530-534,共5页Shanghai Journal of Stomatology

基　　金：甘肃省自然科学基金(17JR5RA260)。

摘　　要：目的:评价自体牙本质颗粒与Bio-Oss骨粉植入引导骨再生治疗牙周骨缺损的效果。方法:选择2018年5月—2020年5月张掖人民医院收治的82例行引导骨再生治疗的牙周骨缺损患者,依照随机数表法分为实验组和对照组,每组41例。对照组植入Bio-Oss骨粉,实验组植入自体牙本质颗粒。比较2组患者牙周袋深度和附着丧失,颊侧软组织剖面、颊侧软组织厚度,红色美学评分,修复成功率及并发症。采用SPSS 22.0软件包对数据进行统计学分析。结果:术后1个月和术后1年,2组患者牙周袋深度和附着丧失均显著降低(P<0.05);且术后1年,2组患者牙周袋深度和附着丧失均低于术后1个月(P<0.05)。术后1个月和术后1年,实验组患者牙周袋深度和附着丧失显著低于对照组(P<0.05)。术后1个月和术后1年,2组患者颊侧软组织剖面显著高于术前(P<0.05);术后1年,2组颊侧软组织剖面显著低于术后1个月(P<0.05)。术后1年,实验组患者颊侧软组织剖面显著高于对照组(P<0.05)。术后1个月和术后1年,2组患者颊侧软组织厚度显著高于术前。各时间点,2组患者颊侧软组织厚度相比,差异无统计学意义(P>0.05)。术后1个月和术后1年,2组患者红色美学评分显著高于术前(P<0.05);且术后1年2组红色美学评分显著高于术后1个月(P<0.05)。术后1个月和术后1年,实验组患者红色美学评分显著高于对照组(P<0.05)。术后1年,实验组和对照组修复成功率分别为90.24%(37/41)和85.37%(35/41),2组修复成功率相比,差异无统计学意义(P>0.05)。2组患者并发症发生率无统计学差异(P>0.05)。结论:自体牙本质颗粒引导骨再生治疗牙周骨缺损患者,能够降低牙周袋深度和附着丧失,提高颊侧软组织剖面和红色美学评分,且修复成功率与Bio-Oss骨粉植入相当,是一种安全可靠的治疗方法。PURPOSE:To analyze the effect of autologous dentin particles and Bio-Oss bone powder implantation on guided bone regeneration in the treatment of periodontal bone defects.METHODS:Eighty-two patients with periodontal bone defect treated in Zhangye People’s Hospital from May 2018 to May 2020 who underwent guided bone regeneration treatment were selected and divided into experimental group and control group according to random number table method,with 41 cases in each group.The control group was implanted with Bio-Oss during the operation,and the experimental group was implanted with autologous dentin particles during operation.Periodontal pocket depth and attachment loss,buc-cal soft tissue profile,buccal soft tissue thickness,red aesthetic score,success rate,and complications were compared between the two groups of patients.SPSS 22.0 software package was used for statistical analysis.RESULTS:Comparison within the group showed that 1 month and 1 year after operation,the periodontal pocket depth and attachment loss of the two groups were significantly reduced(P<0.05);and 1 year after operation,the periodontal pocket depth and attachment loss of the two groups were significantly lower than 1 month after surgery(P<0.05).Comparison between groups showed that1 month and 1 year after operation,the periodontal pocket depth and attachment loss of the experimental group were significantly lower than those of the control group(P<0.05).Comparison within groups showed that 1 month and 1 year after operation,the buccal soft tissue profile of the two groups were significantly higher than that before operation(P<0.05);and 1 year after operation,the buccal soft tissue profile of the two groups were significantly lower than 1 month after operation.Comparison between groups showed that 1 year after operation,the buccal soft tissue profile of the experimental group was significantly higher than that of the control group(P<0.05).Comparison within groups showed that 1 month and1 year after surgery,the thickness of the buccal soft tis

关 键 词：自体牙本质颗粒 Bio-Oss骨粉植入 引导骨再生 牙周骨缺损 

分 类 号：R781.4[医药卫生—口腔医学]