不同无菌操作流程对非手术患者中心静脉导管相关感染发生的影响:回顾性队列研究  

Effects of different aseptic procedures on occurrence of central venous catheter-related infections in non-surgical patients:a retrospective cohort study

作　　者：朱慧慧[1] 张加强[1] 丛旭辉 李宁涛[1] 崔明珠[1] 孙铭阳[1] Zhu Huihui;Zhang Jiaqiang;Cong Xuhui;Li Ningtao;Cui Mingzhu;Sun Mingyang(Department of Anesthesiology and Perioperative Medicine,Henan Provincial People′s Hospital,Zhengzhou 450003,China)

机构地区：[1]河南省人民医院麻醉与围术期医学科,郑州450003

出　　处：《中华麻醉学杂志》2022年第8期901-903,共3页Chinese Journal of Anesthesiology

摘　　要：目的评价无菌操作的严格流程对预防中心静脉导管相关感染的价值。方法对2015年至2019年期间行中心静脉置管术的非手术患者进行回顾性队列研究。按照中心静脉置管术中实施无菌操作的常规流程和严格流程进行分组,2015年至2017年期间患者为常规流程组(C组);2018年至2019年期间患者为严格流程组(E组)。记录置管术后6 d内中心静脉导管相关感染(局部感染、血流感染)的发生情况。结果与C组相比,E组中心静脉导管局部感染发生率降低[1.79%vs.0.48%,P<0.001;其相对危险度为0.27(在0.10~0.30范围内)],而中心静脉导管血流感染发生率差异无统计学意义(0.29%vs.0.19%,P>0.05)。E组中心静脉导管相关感染累积发生率为0.67%(<1.00%)。结论中心静脉置管术中实施无菌操作的严格流程,可进一步降低中心静脉导管相关感染发生,具有显著的临床价值。Objective To evaluate the value of implementing strict aseptic operation procedures in preventing central venous catheter-related infections.Methods This retrospective cohort study consisting of non-surgical patients who underwent central venous catheterization from 2015 to 2019 were conducted.The patients were divided into 2 groups according to routine aseptic procedures and strict aseptic procedures,the patients between 2015 and 2017 served as routine aseptic procedure group(group C),and the patients between 2017 and 2019 served as strict aseptic procedure group(group E).The occurrence of central venous catheter-related infections(local infection,bloodstream infection)was recorded within 6 days after catheterization.Results Compared with group C,the incidence of central venous catheter-related local infection was significantly decreased(1.79%vs.0.48%,P<0.001;the rate ratio being 0.27 ranged in 0.10-0.30),while no significant change was found in the incidence of central venous catheter-related bloodstream infection in group E(0.29%vs.0.19%,P>0.05).The cumulative incidence of central venous catheter-related infections was 0.67%(<1.00%)in group E.Conclusions Implementation of strict aseptic procedures during central venous catheterization can further reduce the occurrence of central venous catheter-related infections,which has significant clinical value.

关 键 词：导管插入术 中心静脉 导管相关性感染 无菌术 队列研究 回顾性研究 

分 类 号：R613[医药卫生—外科学]