甲状腺癌^(131)I治疗后相关唾液腺炎的诊疗进展  

Advances in diagnosis and treatment of sialadenitis associated with thyroid cancer after^(131)I therapy

作　　者：赵佳雄 南欣荣[1] 孟兵[1] 李瑞芳[1] 闫星泉 Zhao Jiaxiong;Nan Xinrong;Meng Bing;Li Ruifang;Yan Xingquan(Department of Oral and Maxillofacial Surgery,The First Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院口腔颌面外科,太原030001

出　　处：《中华口腔医学研究杂志（电子版）》2022年第3期199-202,共4页Chinese Journal of Stomatological Research(Electronic Edition)

摘　　要：^(131)I相关唾液腺炎是甲状腺癌^(131)I治疗后的常见并发症,其主要机理尚未完全明确,研究认为唾液腺导管上皮细胞的钠碘同向转运体(NIS)对碘的吸收,导致导管急性或慢性炎症。最新研究结果显示,该病可能还与水通道蛋白(AQP)有关。^(131)I相关唾液腺炎临床表现及治疗方案基本等同于常规的急慢性唾液腺炎,临床上以预防为主。本文针对近年来对^(131)I相关唾液腺炎病理、生理、诊断及治疗研究进展作一综述。^(131)I⁃related sialadenitis is a common complication after thyroid cancer^(131)I treatment,and its main mechanism is not yet fully understood.Studies suggest that the absorption of iodine by the sodium⁃iodine symporter(NIS)of salivary gland duct epithelial cells leads to acute or chronic inflammation of the duct.The latest research results show that it may also be related to aquaporin(AQP).The clinical manifestations and treatment plan of^(131)I⁃related sialadenitis are basically equivalent to conventional acute and chronic sialadenitis,and prevention is the main clinical treatment.This article reviews the recent research progress on the pathology,physiology,diagnosis and treatment of^(131)I⁃related sialadenitis.

关 键 词：唾液腺炎 碘放射性同位素 甲状腺癌 

分 类 号：R736.1[医药卫生—肿瘤]