神经细胞三维培养技术研究进展  

RESEARCH ADVANCES IN THREE-DIMENSIONAL CULTURE TECHNIQUES FOR NERVE CELLS

作　　者：关冀弛 刘丹 陈艳阁 樊雪 汪海峰 GUAN Jichi;LIU Dan;CHEN Yange;FAN Xue;WANG Haifeng(School of Pharmacy and Bioengineering,Shenyang University of Chemical Technology,Shenyang 110142,China)

机构地区：[1]沈阳化工大学制药与生物工程学院,辽宁沈阳110142 [2]辽宁成大生物股份有限公司

出　　处：《精准医学杂志》2022年第6期554-558,564,共6页Journal of Precision Medicine

基　　金：辽宁省教育厅科学研究经费项目青年科技人才“育苗”项目(LQ2020021)。

摘　　要：神经系统疾病严重威胁人类生命健康,降低了患者的生活质量。神经细胞三维培养技术,可以模拟脑部高度复杂化的三维神经网络结构,清晰展现神经细胞三维空间的生长机制和特点,可以用于揭示神经系统疾病的发生发展过程,也可以用于某些特异性药物的研发。本文对目前神经细胞三维培养技术的研究现状进行了总结与展望。Nervous system diseases seriously threaten human health and reduce patients’quality of life.Three-dimensional culture techniques for nerve cells can simulate the highly complex three-dimensional neural network structure of the brain and clearly display the growth mechanism and characteristics of nerve cells in the three-dimensional space.They can be used to reveal the development and progression of nervous system diseases and can also be used for the research and development of some specific drugs.This article summarizes the current research status of three-dimensional culture techniques for nerve cells and looks into the future of these techniques.

关 键 词：神经元 细胞培养技术 神经系统疾病 综述 

分 类 号：R394.26[医药卫生—医学遗传学] R74[医药卫生—基础医学]