随机质控方案在不同检测系统中的应用  

Application of random quality control scheme in different inspection systems

作　　者：陈倩 单志明[1] 康凤凤[1] 夏俊 叶德力 宋超[1] CHEN Qian;SHAN Zhiming;KANG Fengfeng;XIA Jun;YE Deli;SONG Chao(Zhejiang Clinical Laboratory Center,Zhejiang Provincial People′s Hospital/People′s Hospital of Hangzhou Medical College,Hangzhou,Zhejiang 310014,China;Department of Clinical Laboratory,Zhejiang Provincial People′s Hospital/People′s Hospital of Hangzhou Medical College,Hangzhou,Zhejiang 310014,China)

机构地区：[1]浙江省人民医院/杭州医学院附属人民医院浙江省临床检验中心,浙江杭州310014 [2]浙江省人民医院/杭州医学院附属人民医院检验中心,浙江杭州310014

出　　处：《检验医学与临床》2022年第23期3180-3184,共5页Laboratory Medicine and Clinic

基　　金：浙江省教育厅一般科研项目(Y202044591)。

摘　　要：目的探讨开机质量控制(简称质控)与随机质控的关系,以及随机质控方案在不同检测系统中的应用。方法收集2020年10月至2021年1月该院3台检测系统(AU5830、AU5821、AU5831)双水平(中水平和高水平)的开机质控及随机质控检验结果[共11个常规生化项目,包括清蛋白(Alb)、丙氨酸氨基转移酶(ALT)、尿素(BUN)、钙(Ca)、镁(Mg)、氯(Cl)、钠(Na)、总胆固醇(TC)、葡萄糖(Glu)、肌酐(Crea)、钾(K)]。以<1/3允许总误差(TEa)为标准分别计算开机质控与随机质控检验结果的相对偏差,比较开机质控与随机指控的Z分数、均值、相对偏差。结果钾和钠在3台检测系统上均较为稳定,开机质控与随机质控检验结果无明显差异,其余项目在不同检测系统上结果有差异,开机质控与随机质控检验结果也存在差异。在AU5830上,双水平的Alb均不满足室内质控TEa要求。在AU5821上,双水平的Alb、中水平的Glu和高水平的TC均不满足室内质控TEa要求。在AU5831上,双水平的Glu均不满足室内质控TEa要求。结论随机质控方案可以作为开机质控方案的有效补充,能提高检测精密度,确保检测可靠度,可为临床提供更准确有效的服务。Objective To explore the relationship between startup quality control and random quality control,and the application of random quality control scheme in different detection systems.Methods From October 2020 to January 2021,the startup quality control and random quality control results of 3 testing systems(AU5830,AU5821 and AU5831)at both levels(medium level and high level)were collected,a total of 11 routine biochemical items,including albumin(Alb),alanine aminotransferase(ALT),urea(BUN),calcium(Ca),magnesium(Mg),chlorine(Cl),sodium(Na),total cholesterol(TC),glucose(Glu),creatinine(Crea),potassium(K).Using<1/3 allowable total error(TEa)as the standard,the relative deviation of startup quality control and random quality control was calculated respectively,and the Z-score,mean value and relative deviation of startup quality control and random charge were compared.Results Potassium and sodium were stable in the three detection systems,and there was no significant difference between the startup quality control and random quality control results.The results of other items were different in different detection systems,and the startup quality control and random quality control results were also different.In AU5830,both levels of Alb could not meet the requirements of indoor quality control TEa.On AU5821,dual level of Alb,medium level of Glu and high level of TC could not meet the requirements of indoor quality control TEa.On AU5831,both levels of Glu could not meet the requirements of indoor quality control TEa.Conclusion Random quality control scheme is an effective supplement to boot quality control scheme,which can improve the detection precision,ensure the reliability of detection and provide more accurate and effective services for clinical.

关 键 词：质量控制 随机质量控制 允许总误差 相对偏差 

分 类 号：R-331[医药卫生] R446.1