非酒精性脂肪肝痰湿证代谢特征与致病机制初探  

Metabolic Characteristics and Pathogenic Mechanism of Phlegm-dampness Syndrome of Nonalcoholic Fatty Liver Disease

作　　者：王振雄 李佩芳 李廷荃 WANG Zhenxiong;LI Peifang;LI Tingquan(Shanxi University of Chinese Medicine,Jinzhong 030619,Shanxi,China;Affiliated Hospital of Shanxi University of Chinese Medicine,Taiyuan 030024,Shanxi,China)

机构地区：[1]山西中医药大学,山西晋中030619 [2]山西中医药大学附属医院,山西太原030024

出　　处：《实用中医内科杂志》2022年第9期1-3,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家自然科学基金项目(81874474);山西药茶的研制和开发(2020PY-YC-38)。

摘　　要：非酒精性脂肪肝作为一种常见病,其致病机制与多种因素、作用靶点相关。非酒精性脂肪肝痰湿证存在与实验指标、肠道菌群结构、炎症与免疫细胞因子、FXR受体等方面的密切相关性,通过分析讨论将有助于阐明非酒精性脂肪痰湿证代谢变化特征及致病机制,进一步明确此证型的治疗侧重点,为中医治疗非酒精性脂肪肝提供新的思路及靶点。Non-alcoholic fatty liver disease(NAFLD) is a common disease in the world.It′s pathogenesis is related to many factors and targets. Phlegm-dampness syndrome of non-alcoholic fatty liver is closely related to experimental indicators, intestinal flora structure, inflammation and immune cytokines, FXR receptors, etc. Analysis and discussion will help to clarify the metabolic characteristics and pathogenic mechanism of phlegm-dampness syndrome of non-alcoholic fat, and further clarify the treatment focus of this syndrome type. It provides a new idea and target for traditional Chinese medicine treatment of nonalcoholic fatty liver.

关 键 词：非酒精性脂肪肝 痰湿证 代谢特征 致病机制 

分 类 号：R575.5[医药卫生—消化系统]