欧洲男科学会《Klinefelter综合征指南(2021)》解读与思考  

Interpretation and discussion of 2021 European Academy of Andrology Guidelines on Klinefelter Syndrome

作　　者：魏婕 陈国芳[2] 徐书杭[2] 刘超[2] Jie Wei;Guofang Chen;Shuhang Xu;Chao Liu(Department of Endocrinology,Kunshan Integrated TCM and Western Medicine Hospital,Suzhou 215300,China;Department of Endocrinology,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Traditional Chinese Medicine,Nanjing 210028,China)

机构地区：[1]I昆山市中西医结合医院内分泌科,苏州215300 [2]南京中医药大学附属中西医结合医院内分泌科,江苏省中医药研究院,国家中医药管理局瘿病证治重点研究室,南京210028

出　　处：《中华生殖与避孕杂志》2022年第10期1031-1037,共7页Chinese Journal of Reproduction and Contraception

摘　　要：Klinefelter综合征是最常见的男性性染色体异常性疾病之一,但其病因尚不明确,临床表现多样,诊断率低,且治疗方案具体细则仍存争议。欧洲男科学会于2021年发布了首个《Klinefelter综合征指南》,回顾了Klinefelter综合征的新近研究成果,对其病因、流行病学、筛查及治疗等进行了详细阐述。该指南共有47条推荐条款,涵盖了不同年龄阶段Klinefelter综合征的临床表现、随访项目、筛查及治疗方案的选择,为Klinefelter综合征的规范诊治提供了切实可行的建议。Klinefelter syndrome(KS)is one of the most common male sex chromosome abnormalities with diverse clinical manifestation and low diagnostic rate,though the specific details of treatment options remain controversial.European Academy of Andrology issued guidelines on KS in 2021 for the first time in the world according to recent evidence,and comprehensively described the etiology,epidemiology,screening and treatment of KS.The guideline consists of 47 recommendations covering the scopes of clinical manifestations,follow-up programs,screening and treatment options for KS at different ages,and provides more reasonable and standardized guidance for the management of KS.

关 键 词：KLINEFELTER综合征 筛查 睾酮替代治疗 精子冷冻 睾丸取精术 

分 类 号：R596.1[医药卫生—内科学]