以芋螺毒素为例的生物化学与分子生物学案例教学探索  

Exploration of case method for Biochemistry and Molecular Biology illustrated by the case of conotoxin

作　　者：杨尧 徐尧 卢小玲 王梁华[1] YANG Yao;XU Yao;LU Xiaoling;WANG Lianghua(Department of Biochemistry and Molecular Biology,College of Basic Medical Sciences,Naval Military Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学基础医学院生物化学与分子生物学教研室,上海200433

出　　处：《生命的化学》2022年第9期1752-1756,共5页Chemistry of Life

摘　　要：海洋生物中存在众多的蛋白质类毒素。这些毒素在生物医药、军事领域具有重大的应用前景。芋螺毒素是一种多肽类毒素,其结构、性质与功能的研究紧密联系了生物化学与分子生物学课程中第一章“蛋白质的结构与功能”相关知识点。以芋螺毒素为例开展案例教学,既通过创新教学内容实现了科教融合,提升了课堂效果,又培养了学员在分析问题、解决问题方面的综合能力。在海军医学院校学生的生物化学与分子生物学授课中,融入海洋、军事等背景,符合新时代贯彻习近平强军思想,着眼建设世界一流军队、培养一流军事人才,坚持为战斗力服务,为官兵服务的鲜明导向。There are many protein-based toxins in marine organisms, which have great potential for biomedical and military applications. The study of the structure, properties, and functions of the conotoxin, a kind of polypeptide toxin, is closely connected to the related knowledge points of chapter 1: ″Structure and Functions of Proteins″ in the course of Biochemistry and Molecular Biology. Implementing the case method illustrated by the example of conotoxin, not only realizing the integration of science and education, enhancing the effectiveness of class by innovating teaching contents, but also cultivating the comprehensive ability of the students in analyzing and solving problems. The integration of marine and military backgrounds in the teaching of biochemistry and molecular biology to students at the naval medical school is in line with the new era of implementing Xi Jinping′s thought on strengthening the military, focusing on building a world-class military, cultivating first-class military personnel, and adhering to the distinctive orientation of serving the fighting force and serving the officers and soldiers.

关 键 词：生物化学与分子生物学 案例教学 芋螺毒素 蛋白质 

分 类 号：Q5-4[生物学—生物化学] Q7-4[文化科学—高等教育学] G642[文化科学—教育学]