河南"4.26"60Co源辐射事故一例受照者患非霍奇金淋巴瘤的病因探讨  

Inquire into the etiology of non-Hodgkin lymphoma in a victim of Henan "4.26" 60Co source radiation accident

作　　者：卢志娟 张曼曼 王雯 焦玲[1] 赵风玲 吕玉民 姜恩海[1] 王津晗[1] Lu Zhijuan;Zhang Manman;Wang Wen;Jiao Ling;Zhao Fengling;Lyu Yumin;Jiang Enhai;Wang Jinhan(Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine,Institute of Radiation Medicine,Chinese Academy of Medical Sciences,Tianjing 300192,China;Lymphoma Center,Hospital of Hematology,Institute of Hematology,Chinese Academy of Medical Sciences,Tianjing 300200,China;Occupational Medicine,Henan Institute for Occupational Health,Zhengzhou 450052,China;Toxicology Laboratory,Henan Institute for Occupational Health,Zhengzhou 450052,China)

机构地区：[1]中国医学科学院放射医学研究所,天津市放射医学与分子核医学重点实验室,天津300192 [2]中国医学科学院血液学研究所血液病医院,淋巴瘤诊疗中心,天津300200 [3]河南省职业病防治研究院职业病科,郑州450052 [4]河南省职业病防治研究院毒理研究室,郑州450052

出　　处：《国际放射医学核医学杂志》2022年第9期580-584,共5页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：中国医学科学院医学与健康科技创新工程项目(2021-I2M-1-042)。

摘　　要：关于电离辐射是否可诱发非霍奇金淋巴瘤(NHL), 目前的研究结果尚未获得一致结论。笔者报道了河南"4.26"60Co源辐射事故中1例中度骨髓型急性放射病患者受照后第13年患NHL的病例, 结合患者的受照史、病史特点、诊断及国际多项大型研究, 从流行病学资料和影响因素两方面分析了患者"天"患非霍奇金淋巴瘤与电离辐射的关系, 为电离辐射致NHL提供辐射流行病学依据。As for whether ionizing radiation can induce non-Hodgkin lymphoma(NHL),the current study results have not yet reached a consensus conclusion.The authors reported a case of NHL,who was diagnosed with moderate bone marrow form of acute radiation sickness in Henan"4.26"60Co source radiation accident and suffered from NHL 13 years after exposure.And analyzed from two aspects of epidemiological data and influence factors in combined with the patient's exposure history,characteristics of medical history,diagnosis and many international large-scale studies to provide radiation epidemiology for NHL caused by ionizing radiation.

关 键 词：非霍奇金淋巴瘤 辐射流行病学 电离辐射 病因探讨 病史特点 NHL 骨髓型急性放射病 流行病学资料 

分 类 号：R733.1[医药卫生—肿瘤]