侵袭性前列腺癌诊断中高b值扩散加权成像的应用价值  

The application value of high-b value diffusion weighted imaging in patient with invasive prostate cancer

作　　者：谢良钧 赖林强 夏水伟 王祖飞[1] XIE Liangjun;LAI Linqiang;XIA Shuiwei;WANG Zufei(Department of Radiology,Lishui Central Hospital,Lishui,Zhejiang Province 323300,China;Department of Interventional,Lishui Central Hospital,Lishui,Zhejiang Province 323300,China)

机构地区：[1]丽水市中心医院放射科,浙江丽水323300 [2]丽水市中心医院介入科,浙江丽水323300

出　　处：《实用放射学杂志》2022年第10期1668-1671,共4页Journal of Practical Radiology

摘　　要：目的探讨侵袭性前列腺癌诊断中高b值扩散加权成像(DWI)的应用价值。方法回顾性选取前列腺癌患者111例,根据穿刺标本的Gleason评分分为高危组(Gleason≥8分)和中低危组(Gleason≤7分)。患者均在穿刺前行不同b值下DWI检查。以最终病理结果为标准,根据信号的不同在表观扩散系数(ADC)图上进行ADC值测定。比较不同b值下不同分组的ADC值差异以及不同b值下的诊断效能,并分析ADC值与Gleason评分的相关性。结果2种b值下测得不同前列腺癌分组的ADC值有显著差异(P<0.05);通过绘制受试者工作特征(ROC)曲线分析,2种b值下ADC值鉴别不同分组前列腺癌的曲线下面积(AUC)分别为0.857及0.903,差异有统计学意义(P<0.05);2种b值下ADC值与Gleason评分呈负相关,比较2组间相关系数(ρ),结果显示无显著差异(P>0.05)。结论侵袭性前列腺癌诊断中高b值DWI的诊断效能优于常规b值,能够在一定程度上反映出肿瘤的侵袭性程度以及对其预后进行预测。ObjectiveTo investigate the application value of high-b value diffusion weighted imaging(DWI)in patient with invasive prostate cancer.Methods A total of 1ll patients with prostate cancer were retrospectively selected.According to the Gleason score of the puncture specimens,all patients were divided into two groups,including the high-risk group(Gleason≥8)and medium-low-risk group(Gleason<7).DWI examination with different b values were performed on ll patients before puncture.Taking the result of pathology as gold standard,the apparent diffusion coefficient(ADC)values were measured and recorded on the ADC maps based on the different signals.The different b values were compared to analyze the different ADC values and diagnostic performances between the two groups,and the correlation between ADC value and Gleason score was further analyzed.Results The ADC values with different two b values were significantly different between the two groups with prostate cancer(P<0.05).The ADC values with different two b values were significantly different to identify prostate cancer between the two groups,and the area under the curve(AUC)of receiver operating characteristic(ROC)curve were 0.857 and 0.903,respectively(P<0.05).The ADC values with different two b values were showed the negative correlation with Gleason score.There was no significant difference in p between the two groups(P>0.05).Conclusion The diagnostic performance of high-b value DWl is significantly higher than that of conventional b value DWI in patient with invasive prostate cancer,which can reflect the invasiveness of the prostate cancer and predict its prognosis to a certain extent.

关 键 词：前列腺癌 扩散加权成像 表观扩散系数 GLEASON评分 

分 类 号：R737.25[医药卫生—肿瘤] R445.2[医药卫生—临床医学]