Prognostic values of optic nerve sheath diameter for comatose patients with acute stroke:An observational study  

作　　者：Sha Zhu Chao Cheng Liu-Liu Wang Dian-Jiang Zhao Yuan-Li Zhao Xian-Zeng Liu 

机构地区：[1]Department of Neurology,Peking university international hospital,Beijing 102206,China [2]Department of Radiology,Peking University International Hospital,Beijing 102206,China [3]Department of Intensive Care Unit,Peking University International Hospital,Beijing 102206,China [4]Department of Neurosurgery,China National Clinical Research Center for Neurological Diseases,Beijing Tiantan Hospital,Beijing 100070,China

出　　处：《World Journal of Clinical Cases》2022年第33期12175-12183,共9页世界临床病例杂志

摘　　要：BACKGROUND Optic nerve sheath diameter(ONSD)measurement is one of the non-invasive methods recommended for increased intracranial pressure(ICP)monitoring.AIM This study aimed to evaluate the roles of optic nerve sheath diameter(ONSD)and ONSD/eyeball transverse diameter(ETD)ratio in predicting prognosis of death in comatose patients with acute stroke during their hospitalization.METHODS A total of 67 comatose patients with acute stroke were retrospectively recruited.The ONSD and ETD were measured by cranial computed tomography(CT)scan.All patients underwent cranial CT scan within 24 h after coma onset.Patients were divided into death group and survival group according to their survival status at discharge.The differences of the ONSD and ONSD/ETD ratio between the two groups and their prognostic values were compared.RESULTS The ONSD and ONSD/ETD ratio were 6.07±0.72 mm and 0.27±0.03 in the comatose patients,respectively.The ONSD was significantly greater in the death group than that in the survival group(6.32±0.67 mm vs 5.65±0.62 mm,t=4.078,P<0.0001).The ONSD/ETD ratio was significantly higher in the death group than that in the survival group(0.28±0.03 vs 0.25±0.02,t=4.625,P<0.0001).The area under the receiver operating characteristic curve was 0.760(95%CI:0.637-0.882,P<0.0001)for the ONSD and 0.808(95%CI:0.696-0.920,P<0.0001)for the ONSD/ETD ratio.CONCLUSION The mortality increased in comatose patients with acute stroke when the ONSD was>5.7 mm or the ONSD/ETD ratio was>0.25.Both indexes could be used as prognostic tools for comatose patients with acute stroke.The ONSD/ETD ratio was more stable than the ONSD alone,which would be preferred in clinical practice.

关 键 词：Optic nerve sheath diameter Eyeball transverse diameter COMA Intracranial pressure STROKE PROGNOSIS 

分 类 号：R743.3[医药卫生—神经病学与精神病学]