Acute cytomegalovirus hepatitis in an immunocompetent patient:A case report  

作　　者：Jack P Wang Bou-Zenn Lin Chih-Lin Lin Kuan-Yang Chen Tsung-Jung Lin 

机构地区：[1]Department of Gastroenterology,Taipei City Hospital,Taipei City 10629,Taiwan [2]University of Taipei,Taipei City 10066,Taiwan

出　　处：《World Journal of Clinical Cases》2022年第34期12605-12609,共5页世界临床病例杂志

摘　　要：BACKGROUND Cytomegalovirus(CMV)infection is usually subclinical and asymptomatic in the healthy population,whereas severe complications occur in immunocompromised patients.CASE SUMMARY In this case report,we described a rare case of acute CMV hepatitis in a 35-yearold male immunocompetent patient who presented with a history of week-long intermittent fever with nonspecific constitutional symptoms.Acute hepatitis was suspected according to the initial serological tests.After ruling out other etiologies,including viral hepatitis A,B,C,drug,alcohol,autoimmune,and Wilson disease,acute CMV hepatitis was diagnosed based on positive CMV IgM and DNA quantitative tests.Because there was no any local acute hepatitis E reported in Taiwan,so hepatitis E was not checked.The patient recovered both clinically and serologically with symptomatic management and without antiviral therapy within 12 days from the onset of symptom.CONCLUSION In conclusion,a diagnosis of CMV infection should be considered when nonspecific prodromal symptoms occur in acute hepatitis with an uncertain etiology.Antiviral therapy should not be used in immunocompetent patient who had no decompensation of the liver,such as this patient.Widely available noninvasive tests for CMV can facilitate early diagnosis if used appropriately.Harm–benefit analysis is essential before using antiviral therapy in immunocompetent patients.

关 键 词：CYTOMEGALOVIRUS Acute hepatitis IMMUNOCOMPETENT Case report 

分 类 号：R512.6[医药卫生—内科学]