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Generation,interrogation,and future applications of microglia-containing brain organoids: 《Neural Regeneration Research》2025年第12期3448-3460,共13页Julia Di Stefano Federica Di Marco Ilaria Cicalini Una FitzGerald Damiana Pieragostino Marleen Verhoye Peter Ponsaerts Elise Van Breedam; funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skodowska-Curie grant agreement No.813263(PMSMat Train,granted to UF,PP,MV,and DP);provided by the Fund for Scientific Research Flanders(FWO-Vlaanderen)of the Flemish Government(FWO sabbatical bench fee K800224N granted to PP)and ERA-NET Re Park(granted to PP)。; Brain organoids encompass a large collection of in vitro stem cell–derived 3D culture systems that aim to recapitulate multiple aspects of in vivo brain development and function.First,this review provides a brief int...; 关键词：3D cell culture brain organoids immune response immunocompetent model in vitro model MICROGLIA neural organoids NEUROIMMUNOLOGY neuroinflammation

Disseminated liver histoplasmosis in an immunocompetent individual cured by liver transplantation and voriconazole from China:A case report: 《World Journal of Gastroenterology》2025年第9期146-153,共8页Chen-Xuan Li Hao-Dong Chen Shakoor Kashif Bin Xie Jing Luo Ting Li; BACKGROUND Histoplasmosis is a rare infectious condition with mainly pulmonary involvement which is generally self-limiting in immunocompetent individuals.Its manifestation varies and lacks specificity.This study repo...; 关键词：HISTOPLASMA Disseminated histoplasmosis IMMUNOCOMPETENCE Liver transplantation VORICONAZOLE Case report

Report and Management of a Rare Case of Listeria monocytogenes Meningitis in an Immunocompetent Child in Cameroon: 《Open Journal of Medical Microbiology》2024年第4期225-229,共5页Tchuinte Pierrette Landrie Simo Magne Larissa Tagne Jean Taguebue William Mbanzouen Marcelle Abanda Esther Sokeng Harley Ndamukong Laurence Noubissi-Jouegouo Jean Romain Mbe Flaubert Tassadjo Manuella Ango Cedric Thierry Roland Fouda Urbaine Ngon Ariane Nzouankeu Minone Rosanne Ngome; Bacterial meningitis, due to Listeria monocytogenes, is an invasive central nervous infection, commonly reported in high-risk subjects such as pregnant women, infants, the elderly and immunocompromised patients. Howev...; 关键词：Listeria monocytogenes MENINGITIS IMMUNOCOMPETENT

A Rare Case of Herpetic Esophagitis in an Immunocompetent Patient with No Risk Factors: 《Open Journal of Gastroenterology》2024年第11期395-401,共7页Athanasios Kontos George Sachtouris Ioannis Tziortziotis Evelina Skafida Evaggelia Boti Dimitrios Dimitroulopoulos; Introduction: Herpetic esophagitis (HE) is an esophageal infection caused by herpes simplex virus (HSV). It commonly occurs in immunosuppressive patients but rarely affects immunocompetent people. It presents with ody...; 关键词：Herpetic ESOPHAGITIS IMMUNOCOMPETENT Risk Factors

Varicella-Zoster Virus Encephalitis with Hyponatremia in an Immunocompetent Elderly Patient:A Case Report: 《Journal of Clinical and Nursing Research》2024年第9期53-58,共6页Luxuan Yang Wenyong Zhang Xiujuan Shen Meiqi Liu Dan Xiao; As a common cause of viral encephalitis,varicella-zoster virus(VZV)may invade the central nervous system of immunosuppressed patients during reactivation.Herein,we report a rare case of an immunocompetent patient with...; 关键词：Varicella-zoster virus encephalitis IMMUNOCOMPETENT HYPONATREMIA

A Case Report of Bartonella henselae Infection Causing Fever of Unknown Origin: Unveiling a Stealthy Pathogen: 《Open Journal of Internal Medicine》2024年第3期269-277,共9页Neeladri Misra; Bartonella species are bacterial pathogens responsible for Cat Scratch Disease (CSD) with various clinical manifestations, ranging from self-limiting febrile illnesses to severe systemic infections. Diagnosis is often...; 关键词：Bartonella henselae Cat Scratch Disease LYMPHADENOPATHY IMMUNOCOMPETENT Cat ENDOCARDITIS DOXYCYCLINE RIFAMPIN

Mycoplasma hominis Pneumonia Presented as a Cavitary Mass with a Halo Sign in an Immunocompetent Adult Male:A Case Report: 《Infectious Diseases & Immunity》2024年第3期142-145,共4页Pan-Pan Xie Yao Yao Ning Yang Wen-Kai Niu Xin Yuan; supported by the Top-Notch Project for Youth Training(20QNPY115).; Mycoplasma hominis is an opportunistic microorganism that colonizes the genitourinary tract and causes genitourinary infections.However,pulmonary infections caused by M.hominis have rarely been reported in immunocompe...; 关键词：M.hominis Halo sign Cavitary pneumonia Extragenital infections Case report

Modeling human gastric cancers in immunocompetent mice: 《Cancer Biology & Medicine》2024年第7期553-570,共18页Weihong Zhang Shilong Wang Hui Zhang Yan Meng Shi Jiao Liwei An Zhaocai Zhou; supported by the National Key R&D Program of China(Grant No.2020YFA0803200 and 2023YFC2505903);National Natural Science Foundation of China(Grant Nos.82003014,31930026,81972876,82150112,92168116,81725014,81822035,and 82222052);China Postdoctoral Science Foundation(Grant No.2020M671231);Fundamental Research Funds for the Central Universities(Grant No.22120240327)。; Gastric cancer(GC)is a major cause of cancer-related mortality worldwide.GC is determined by multiple(epi)genetic and environmental factors;can occur at distinct anatomic positions of the stomach;and displays high het...; 关键词：Gastric cancer HETEROGENEITY mouse model GEMM IMMUNOCOMPETENT

Septic shock due to Capnocytophaga canimorsus treated with IgM-enriched immunoglobulin as adjuvant therapy in an immunocompetent woman: 《Journal of Intensive Medicine》2024年第2期265-268,共4页Josephine Braunsteiner Stephanie Siedler Dominik Jarczak Stefan Kluge Axel Nierhaus; Background Capnocytophaga canimorsus(C.canimorsus)belongs to the family Flavobacteriaceae.It is a facultative anaerobic Gram-negative bacillus and belongs to the normal oral microbiota of some mammals,such as cats and...; 关键词：belongs enriched SCRATCH

Meningoencephalitis due to Listeria monocytogenes in a Young Immunocompetent Patient: Case Report with Literature Review: 《Advances in Infectious Diseases》2024年第1期213-219,共7页Janette Alejandra Gamiño Gutierrez Gustavo Adolfo Hernández Valdez Arleth Anahí Montaño Gómez Jorge Morales Rojas Graciela Gaddy Robles Martinez Anahi Herrera Ruelas Alin Kaori Ferreyra Gudiño Jocelin Celeste Jurado Cardona Jimena Jexabeth Ibáñez Núñez Anahí Fierros Ramos; Meningoencephalitis secondary to Listeria monocytogenes (L. monocytogenes) mainly affects newborns, the elderly and immunocompromised people;there are extremely rare cases in which said infection occurs in immunocompe...; 关键词：MENINGITIS ENCEPHALITIS Rhombencephalitis Listeria monocytogenes IMMUNOCOMPETENT

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