funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skodowska-Curie grant agreement No.813263(PMSMat Train,granted to UF,PP,MV,and DP);provided by the Fund for Scientific Research Flanders(FWO-Vlaanderen)of the Flemish Government(FWO sabbatical bench fee K800224N granted to PP)and ERA-NET Re Park(granted to PP)。
Brain organoids encompass a large collection of in vitro stem cell–derived 3D culture systems that aim to recapitulate multiple aspects of in vivo brain development and function.First,this review provides a brief int...
Neuroimmunology is an interdisciplinary branch of biomedical science that emerges from the intersection of studies on the nervous system and the immune system.The complex interplay between the two systems has long bee...
supported by R01NS121067.E.A.M.is also supported by R21NS133561 and R21DC021260.
Numerous pathogens can infect the olfactory tract,yet the pandemic caused by SARS-CoV-2 has strongly emphasized the importance of the olfactory mucosa as an immune barrier.Situated in the nasal passages,the olfactory ...
Objective: To investigate the occurrence of PTSD in pre-hospital emergency nurses and its related factors, and to compare the differences of neurotransmitter and immune-related factors between pre-hospital emergency n...
The modern view of the immune system as a sensitizing and modulating machinery of the central nervous system is now well recognized.However,the specific mechanisms underlying this fine crosstalk have yet to be fully d...
In an abstract sense,the immune system is tasked to monitor and interpret insults and potential threats from the external world and mount appropriate defensive actions accordingly.At the same time,it also monitors sta...
The Chiu Lab is supported by NIH grants R01 DK127257 and R01 AI168005,Kenneth Rainin Foundation,Burroughs Wellcome Fund,Food Allergy Science Initiative,Chan-Zuckerberg Initiative,Fairbairn Lyme Initiative,Drako Family Foundation,and Jackson-Wijaya Research Fund.
The gastrointestinal tract is densely innervated by the peripheral nervous system and populated by the immune system.These two systems critically coordinate the sensations of and adaptations to dietary,microbial,and d...
Recent research in neuroimmunology has revolutionized our understanding of the intricate interactions between the immune system and the central nervous system(CNS).The CNS,an“immune-privileged organ”,is now known to...
supported by Shanghai Shuguang Plan Project,No. 18SG15;Shanghai Outstanding Young Scholars Project;Shanghai Talent Development Project,No. 2019044;Clinical Research Plan of SHDC,No. SHDC 2020CR2027B (all to SC)。
Anti-IgLON5 disease is a recently defined autoimmune disorder of the nervous system associated with autoantibodies against IgLON5. Given its broad clinical spectrum and extremely complex pathogenesis, as well as diffi...
The concept of immune privilege suggests that the central nervous system is isolated from the immune system.However,recent studies have highlighted the borders of the central nervous system as central sites of neuro-i...