Background Antibiotic therapy in infertility management is one of the most frequent and useful practices in sub-Saharan setting. Infertility of tubal origin and secondary to infections are the most prevalent. The curr...
Bartonella species are bacterial pathogens responsible for Cat Scratch Disease (CSD) with various clinical manifestations, ranging from self-limiting febrile illnesses to severe systemic infections. Diagnosis is often...
Bullous pemphigoid (BP) is the most prevalent autoimmune sub-epidermal blistering disease that affects mainly the elderly and could lead to serious morbidity. It has numerous risk factors and triggers, including an ag...
Objective:To measure the effect of doxycycline on inflammatory marker[IL-6,TNF-α,ferritin and C reactive protein(CRP)]levels in patients with dengue infection.Methods:A single-centre,open-label,parallel-group randomi...
Background: Due to worldwide increases in the prevalence of antibiotic-resistant bacteria, it is necessary to develop an active drug delivery system that can enable therapeutics to reach their molecular targets. Maint...
Rationale:Fever with myositis and rhabdomyolysis is a medical emergency requiring prompt diagnosis and management.Scrub typhus associated myositis with rhabdomyolysis is rare.Patient concerns:A 36-year-old female pres...
Background:The appropriate antibiotic treatment for severe scrub typhus,a neglected but widespread reemerging zoonotic infection,is unclear.Methods:In this multicenter,double-blind,randomized,controlled trial,we compa...
Background: One of the deadliest parasite infections is malaria. A combination of quinine sulphate and doxycycline is another therapeutic option for malaria that is resistant to chloroquine and is anticipated to be ab...
[Objectives]This study was conducted to compare the accuracy and detection speed of high performance liquid chromatography for determining the content of doxycycline hydrochloride in doxycycline hydrochloride soluble ...
the grants from the National Natural Science Foundation of China(Nos.31100545 and 31670848);the Natural Science Foundation of Guangdong Province(Nos.2016A030313087 and 2022A1515011158).
As a neuropeptide pituitary adenylate cyclase-activating polypeptide(PACAP)-preferring receptor,PAC1-R mediates effective neuroprotective activity.Based on the finding that the antibiotic doxycycline(DOX)with clinical...