Bullous Pemphigoid Induced by Doxycycline: Case Report and Literature Review  

作　　者：Mishal Al Mebayadh Rahaf Aldawish Sohail A. Butt Abdulrahman Saad Aljahhan Mishal Al Mebayadh;Rahaf Aldawish;Sohail A. Butt;Abdulrahman Saad Aljahhan(Dermatology Department, Imam Abdulrahman Bin Faisal University-National Guard Hospital, Dammam, Saudi Arabia;Dermatology Department, Al Rass General Hospital, Al-Qassim, Saudi Arabia;Pathology Department, Dammam Regional Laboratory & Blood Bank, MOH, Dammam, Saudi Arabia;Clinical Documentation Improvement (CDI), Dammam Health Network, Dammam, Saudi Arabia)

机构地区：[1]Dermatology Department, Imam Abdulrahman Bin Faisal University-National Guard Hospital, Dammam, Saudi Arabia [2]Dermatology Department, Al Rass General Hospital, Al-Qassim, Saudi Arabia [3]Pathology Department, Dammam Regional Laboratory & Blood Bank, MOH, Dammam, Saudi Arabia [4]Clinical Documentation Improvement (CDI), Dammam Health Network, Dammam, Saudi Arabia

出　　处：《Case Reports in Clinical Medicine》2024年第5期187-192,共6页临床医学病理报告（英文）

摘　　要：Bullous pemphigoid (BP) is the most prevalent autoimmune sub-epidermal blistering disease that affects mainly the elderly and could lead to serious morbidity. It has numerous risk factors and triggers, including an aging population with several comorbidities and drug exposure. In the published paper, we reported a case about a 32 years old male patient with unknown medical conditions who presented with erythematous patches and plaques on the scalp, face, and trunk with scattered blisters two weeks after initiating doxycycline treatment for folliculitis. The exact pathogenesis of the drug-reaction in drug- associated bullous pemphigoid (DABP) remains controversial. In conclusion, it is crucial for clinicians to be aware of DABP when prescribing doxycycline. The purpose of this case report is to raise awareness of the possible association between bullous pemphigoid and doxycycline.Bullous pemphigoid (BP) is the most prevalent autoimmune sub-epidermal blistering disease that affects mainly the elderly and could lead to serious morbidity. It has numerous risk factors and triggers, including an aging population with several comorbidities and drug exposure. In the published paper, we reported a case about a 32 years old male patient with unknown medical conditions who presented with erythematous patches and plaques on the scalp, face, and trunk with scattered blisters two weeks after initiating doxycycline treatment for folliculitis. The exact pathogenesis of the drug-reaction in drug- associated bullous pemphigoid (DABP) remains controversial. In conclusion, it is crucial for clinicians to be aware of DABP when prescribing doxycycline. The purpose of this case report is to raise awareness of the possible association between bullous pemphigoid and doxycycline.

关 键 词：Bullous Pemphigoid DOXYCYCLINE Drug-Associated Bullous Pemphigoid 

分 类 号：R75[医药卫生—皮肤病学与性病学]