以戴斯相似系数作为评估参数的自动勾画技术用于胃和十二指肠的可靠性  

Reliability of automatic contouring with Dice similarity coefficient as an evaluation parameter for stomach and duodenum

作　　者：马秀瑞 张建英 李婷婷 张玉洁 肖寒 孙菁 吴泇俣 嵇卫星 MA Xiu-rui;ZHANG Jian-ying;LI Ting-ting;ZHANG Yu-jie;XIAO Han;SUN Jing;WU Jia-yu;JI Wei-xing(Department of Radiation Oncology,Zhongshan Hospital,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院放疗科,上海200032

出　　处：《复旦学报（医学版）》2022年第6期948-954,共7页Fudan University Journal of Medical Sciences

基　　金：复旦大学附属中山医院青年科学基金(2021ZSQN26)。

摘　　要：目的研究不同类型的剂量限值与评估自动勾画结果的戴斯相似系数(Dice similarity coefficient,DSC)的关系,分析将自动勾画技术用于放疗的可靠性。方法收集2019年3月至2021年3月内43例接受过上腹部放疗的患者图像,基于RTOG指南以及AccuContour系统,分别对胃和十二指肠进行人工和自动勾画,共得到40例胃部和38例十二指肠的勾画结果。统计各样本的DSC,分析其与剂量体积直方图曲线(dose volume histogram,DVH)参数的差异及平均剂量差异及最大剂量差异的关系。结果DVH参数差异和平均剂量差异随着DSC的增加而减小。DSC>0.95以后,DVH参数和平均剂量的差异将分别缩小至5%和2 Gy。DSC对最大剂量差异大小的预测结果较差。结论DSC本身不足以保证自动勾画技术用于放疗的可靠性,需要进一步评估该技术导致的各类型剂量参数差异。Objective To study the relationship between different types of dose constraints and Dice similarity coefficient(DSC)for evaluating automatic contouring results,and to analyze the reliability of automatic contouring with DSC as evaluation parameter in radiotherapy.Methods A total of 43 patients who had received upper abdominal radiotherapy from Mar 2019 to Mar 2021 were collected.Based on the RTOG guidelines and AccuContour system,the stomach and duodenum were manually and automatically contoured,and the contouring results of 40 cases of stomach and 38 cases of duodenum were obtained.The relationship between DSC and the differences of dose volume histogram(DVH)parameter difference,average dose difference and maximum dose were analyzed.Results The differences of DVH parameter and average dose decreased with the increase of DSC.When DSC was greater than 0.95,the difference of DVH parameter and average dose reduced to 5%and 2 Gy,respectively.DSC had a poor effect on the prediction for the difference of maximum dose.Conclusion It was found that DSC itself was not enough to ensure the reliability of automatic contouring technology in radiotherapy.Therefore,we need to further evaluate the differences of various types of dose parameters caused by this technology.

关 键 词：深度学习 放射治疗 自动勾画 戴斯相似系数(DSC) 剂量限值 

分 类 号：R730.55[医药卫生—肿瘤]