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作 者:王海丽[1] 朱卫平[1] 陆晨晨 Wang Haili;Zhu Weiping;Lu Chenchen(Jiujiang First People's Hospital,Jiujiang City,Jiangxi Province,332000,China)
机构地区:[1]九江市第一人民医院,江西省九江市332000
出 处:《现代电生理学杂志》2022年第4期235-238,共4页Journal of Modern Electrophysiology
摘 要:目的:研究轻度认知损害老年患者采用多导睡眠图监测的变化特点。方法:临床纳入2021年5月至2022年5月期间九江市第一人民医院收治的20例轻度认知损害老年患者作为观察组,性别不限,年龄61~83岁,病程6个月至8年。另选取同期进行体检的20例健康老年人作为对照组。所有研究对象均给予多导睡眠图进行全夜监测,观察轻度认知损害老年患者多导睡眠图的变化特点,及两组研究对象的睡眠质量和心理症状情况。结果:观察组睡眠进程总记录时间、睡眠总时间、睡眠效率和睡眠维持率明显低于对照组,醒起时间、觉醒时间、运动觉醒时间、觉醒次数以及觉睡比明显高于对照组,差异均有统计学意义(P<0.001)。观察组睡眠第1阶段大于对照组,第2阶段和第3阶段小于对照组(P<0.001)。观察组REM睡眠活动度、REM睡眠强度以及REM睡眠密度均大于对照组(P<0.001)。观察组PSQI和SCL-90评分均高于对照组(P<0.001)。结论:轻度认知损害老年患者的多导睡眠图具有深度睡眠减少的特点,可能会导致认知功能进一步退化,加重病情进展。Objective:To study the characteristics of polysomnography monitoring in elderly patients with mild cognition disorders.Methods:A total of 20 elderly patients with mild cognition disorders admitted to Jiujiang First People's Hospital from May 2021 to May 2022 were enrolled as the observation group,both of sexes,aged 61-83 years,and course of disease ranging from 6 months to 8 years.Another 20 healthy elderly patients who underwent physical examination during the same period were selected as the control group.All subjects were monitored with polysomnography overnight to observe the change characteristics of polysomnography in the elderly patients with mild cognitive impairment,as well as the sleep quality and psychological symptoms were observed.Results:The total recording time of sleep progress,total sleep time,sleep efficiency and sleep maintenance rate in the observation group were significantly lower than those in the control group,while the early morning awakening time,awake time,movement awake time,number of wake after sleep onset and ratio of awake and times to sleep all were significantly higher than those in the control group(P<0.001).The REM sleep activity,REM sleep intensity and REM sleep density in the observation group were higher than those in the control group(P<0.001).Pittsburgh sleep quality index and symptom check list-90 scores in the observation group were higher than those in the control group(P<0.001).Conclusion:Polysomnogram in elderly patients with mild cognition disorders is characterized by reduced deep sleep,which may lead to further deterioration of cognitive function and aggravate the progression of the disease.
分 类 号:R741.044[医药卫生—神经病学与精神病学]
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