荧光碳点探针用于甲苯磺酸妥舒沙星的快速检测  

Rapid Determination of Tosufloxacin Tosylate by Fluorescent Carbon Dots Probe

作　　者：郝静静 崔华莉[1] 孙雪花[1] 杨永琳 杨娜 李青姝 Hao Jingjing;Cui Huali;Sun Xuehua;Yang Yonglin;Yang Na;Li Qingshu(Yan'an Key Laboratory of Green Synthetic Materials and Chemical Safety Testing,College of Chemistry and Chemical Engineering,Yan'an University,Yan'an 716000,China)

机构地区：[1]延安大学化学与化工学院延安市绿色合成材料与化学安全检测重点实验室,陕西延安716000

出　　处：《广东化工》2022年第22期189-191,共3页Guangdong Chemical Industry

基　　金：陕西省教育厅重点科学研究项目(20JS154);2020年国家大学生创新训练项目(202010719044)。

摘　　要：在pH=7.20的Tris-HCl缓冲溶液中,阴离子表面活性剂十二烷基硫酸钠(SDS)的增敏作用下,以荧光碳点为探针建立了测定甲苯磺酸妥舒沙星的荧光增敏新方法。实验发现,甲苯磺酸妥舒沙星浓度与体系荧光增敏强度呈良好线性关系,线性范围为3.0~120μg/mL,检出限为0.05μg/mL,回收率为99.19%~100.2%。该法操作简单、快速、具有较好的选择性,可用于药物中甲苯磺酸妥舒沙星含量的测定。In Tris-HCl buffer solution of pH=7.20,A new fluorescence sensitization method for the determination of tosufloxacin tosylate was developed using fluorescent carbon dots as probe with the anionic surfactant sodium dodecyl sulfate(SDS).The experiment found that the concentration of tosufloxacin tosylate and the system fluorescence sensitization intensity,with a linear range of 3.0 to 120μg/mL,the detection limit of 0.05μg/mL,and a recovery rate of 99.17%to 100.2%.The method is simple,rapid and has good selectivity.It can be used for the determination of tosufloxacin tosylate sulfonate in medicine.

关 键 词：荧光探针 碳点 甲苯磺酸妥舒沙星 荧光增敏 

分 类 号：O657[理学—分析化学]