胃癌根治术后早期肠内营养支持对肠功能恢复的影响  

Early Enteral Nutrition Supports the Recovery of Intestinal Function after Radical Gastrectomy

作　　者：罗兴 LUO Xing(Shenyang 739 Hospital,Shenyang,Liaoning Province,Shenyang 110034,China)

机构地区：[1]沈阳七三九医院,辽宁沈阳110034

出　　处：《中国医药指南》2022年第34期103-105,共3页Guide of China Medicine

摘　　要：目的 探讨胃癌根治术后应用早期肠内营养支持对患者肠功能的影响情况。方法 选取2018年9月至2019年12月我院收治的90例胃癌患者作为本次研究对象,利用随机数字表法分组。对照组45例术后予以全肠外营养支持,研究组45例术后予以肠外营养支持联合早期肠内营养支持。对比两组的肠功能、免疫指标、营养状态、并发症情况。结果 研究组胃癌根治术患者术后肠鸣音恢复时间、术后肛门首次排气时间均少于对照组(均P<0.05);两组营养支持前IgA、IgG、IgM、CD_(3)^(+)、CD_(4)^(+)、CD_(8)^(+)等指标对比均P>0.05,营养支持后研究组IgA、IgG、IgM、CD_(3)^(+)、CD_(4)^(+)、CD_(8)^(+)等指标提高幅度较对照组更优(P<0.05);两组营养支持前Alb、PAB、BMI水平对比P>0.05,营养支持后两组Alb、PAB、BMI水平均较营养支持前明显改善,且研究组上述指标均优于对照组,P<0.05;研究组术后并发症发生率(6.67%)低于对照组(24.44%),P<0.05。结论 针对胃癌根治术患者术后早期予以肠内营养支持有利于促进其尽快恢复肠功能,对提高机体免疫力、降低术后并发症发生率也具有积极意义。Objective To investigate the effect of early enteral nutrition support on patients'intestinal function after radical gastrectomy.Methods From September 2018 to December 2019 as the study interval,Ninety gastric cancer patients admitted to our hospital in the above interval were selected as the study object,and grouped by random number table method.Forty-five patients in the control group received total parenteral nutrition support after surgery,and 45 cases in the study group received parenteral nutrition support combined with early enteral nutrition support.The intestinal function,immune indexes,nutritional status,and complications of the two groups were compared.Results The recovery time of bowel sounds and the first exhaust time of anus after radical gastrectomy in the study group were less than those in the control group(all P<0.05).Before and after nutritional support,IgA,IgG,IgM,CD_(3)^(+),CD_(4)^(+),CD_(8)^(+)and other indicators in the two groups were compared,all of which were P>0.05.After nutritional support,IgA,IgG,IgM,CD_(3)^(+),CD_(4)^(+),CD_(8)^(+)and other indicators in the study group had better than those in the control group(P<0.05).The Alb,PAB and BMI levels of the two groups before nutritional support were compared at P>0.05.The levels of Alb,PAB and BMI in the two groups were significantly improved compared with those before nutritional support,and the above indicators in the study group were better than those in the control group,P<0.05.The incidence of postoperative complications in the study group(6.67%)was lower than that in the control group(24.44%).Conclusion Early enteral nutrition support for gastric cancer patients after radical gastrectomy is conducive to promoting the recovery of intestinal function as soon as possible.

关 键 词：胃癌根治术 早期肠内营养支持 肠功能 免疫功能 预后 

分 类 号：R735[医药卫生—肿瘤]