卒中后抑郁的功能性磁共振成像和结构性磁共振成像研究进展  

Research progress of post-stroke depression based on functional magnetic resonance imaging and structural magnetic resonance imaging

作　　者：于红霞 张平[1] 张朝辉 闫海清[1] 贵永堃[1] 苏静 朱瑞瑞 宋景贵[2] YU Hongxia;ZHANG Ping;ZHANG Zhaohui;YAN Haiqing;GUI Yongkun;SU Jing;ZHU Ruirui;SONG Jinggui(Department of Neurology,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China;Department of Neurology,the Second Affiliated Hospital of Xinxiang Medical University,Xinxiang 453005,Henan Province,China)

机构地区：[1]新乡医学院第一附属医院神经内科,河南卫辉453100 [2]新乡医学院第二附属医院神经内科,河南新乡453005

出　　处：《新乡医学院学报》2022年第12期1173-1177,共5页Journal of Xinxiang Medical University

基　　金：国家自然科学基金面上项目(编号:81471349);河南省重点研发与推广专项(科技攻关)项目(编号:192102310347);河南省生物精神病学重点实验室关于2019年度开放课题(编号:ZDSYS2019005)。

摘　　要：目前,卒中后抑郁(PSD)发病机制不明。结构性及功能性磁共振成像为PSD相关临床研究提供了丰富且有价值的依据,可反映大脑形态、功能的变化,从而为早期发现并诊断、治疗PSD提供帮助。目前,抑郁的相关研究主要集中在原发性抑郁,而对于PSD的影像学相关研究相对较少。本文就PSD的结构性和功能性磁共振成像研究进展进行综述。At present,the pathogenesis of post-stroke depression(PSD)is unknown.Structural and functional magnetic resonance imaging provide rich and valuable basis for clinical research on PSD,which can reflect changes in brain morphology and function,thus providing help for early detection,diagnosis and treatment of PSD.At present,researches on depression are mainly focused on primary depression,while researches on the imaging of PSD are relatively few.This article reviews the research progress of structural and functional magnetic resonance imaging in PSD.

关 键 词：卒中后抑郁 结构性磁共振成像 扩散张量成像 功能性磁共振成像 脑网络 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R749.4[医药卫生—临床医学]