腹腔镜肝切除联合冷循环射频消融治疗肝脏多发性肿瘤的效果  

Effect of Laparoscopic Hepatectomy Combined with Cold-Circulation Radiofrequency Ablation in Treatment of Multiple Liver Tumors

作　　者：刘继鹏 郭祥峰[1] 杨岩 Liu Ji-peng;Guo Xiang-feng;Yang Yan(Department of Hepatobiliary Surgery,Shanxian Central Hospital,Heze 274300,Shandong Province,China)

机构地区：[1]单县中心医院肝胆外科,山东菏泽274300

出　　处：《中外医药研究》2022年第6期36-38,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:观察腹腔镜肝切除联合冷循环射频消融治疗肝脏多发性肿瘤的效果。方法:选取2019年1月-2022年1月单县中心医院收治的肝脏多发性肿瘤患者80例为观察对象,按照随机数字表法将其分为观察组和对照组,各40例。对照组采用腹腔镜肝切除手术治疗,观察组采用腹腔镜肝切除联合冷循环射频消融治疗,比较两组患者的各时间点心率(HR)及平均动脉压(MAP),术后认知功能障碍评分(MMSE)、清醒时间、拔管时间、术后认知功能障碍(POCD)发生率、住院时间,生化指标及不良反应发生率。结果:手术开始切肝、切肝完成时,观察组HR低于对照组,MAP高于对照组,差异有统计学意义(P<0.05)。术后1、3、7 d,观察组MMSE评分高于对照组,差异有统计学意义(P<0.05);观察组POCD发生率与住院天数优于对照组,差异有统计学意义(P<0.05);术后,观察组血红蛋白高于对照组,白细胞计数水平优于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜肝切除联合冷循环射频消融治疗肝脏多发性肿瘤的临床效果显著,可改善术后认知功能,减少住院时间,改善生化指标,降低不良反应发生率。Objective:To observe the effect of laparoscopic hepatectomy combined with cold-circulation radiofrequency ablation in the treatment of multiple liver tumors.Methods:Eighty patients with multiple liver tumors who admitted to Shanxian Central Hospital from January 2019 to January 2022 were selected as the observation subjects and divided into the observation group and the control group according to random digital number table method,with 40 cases in each group.The control group was treated with laparoscopic hepatectomy,while the observation group was treated with laparoscopic hepatectomy combined with coldcirculation radiofrequency ablation.Heart rate(HR)and mean arterial pressure(MAP)at each time point,postoperative cognitive dysfunction score by mini-mental state examination(MMSE),awake time,extubation time,incidence of postoperative cognitive dysfunction(POCD),hospitalization time,biochemical indicators and incidence of adverse reactions were compared between the two groups.Results:At the beginning of hepatectomy and upon the completion of hepatectomy,HR in the observation group was lower than that in the control group,MAP in the observation group was higher than that in the control group,and the differences were statistically significant(P<0.05).At 1,3 and 7 days after surgery,the MMSE scores in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of POCD and days of hospitalization in the observation group were better than those in the control group,and the differences were statistically significant(P<0.05).After surgery,the hemoglobin in the observation group was higher than that in the control group,and the level of white blood cell count was lower than that in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic hepatect

关 键 词：腹腔镜肝切除 射频消融 肝脏多发性肿瘤 

分 类 号：R73[医药卫生—肿瘤]