前庭性偏头痛相关基因的研究进展  

Research progress of genes related to vestibular migraine

作　　者：韦东瑶 安宁 鞠琦 李源 田依凡 张雪艳 祝传禛 孔非梦 杨印东 WEI Dongyao;AN Ning;JU Qi;LI Yuan;TIAN Yifan;ZHANG Xueyan;ZHU Chuanzhen;KONG Feimeng;YANG Yindong(Mudanjiang Medical University,Heilongjiang,Mudanjiang 157000,China;Department of Neurology,Hongqi Hospital Affiliated to Mudanjiang Medical University,Heilongjiang,Mudanjiang 157000,China)

机构地区：[1]牡丹江医学院,黑龙江牡丹江157000 [2]牡丹江医学院附属红旗医院神经内科,黑龙江牡丹江157000

出　　处：《中国医药科学》2022年第22期54-57,共4页China Medicine And Pharmacy

摘　　要：前庭偏头痛(VM)是一种急性前庭综合征,被认为是复发性眩晕最常见的原因之一,眩晕发作时可能出现自发性或体位性眩晕、视觉引起的眩晕及视物模糊等临床表现,其主要诊断依据是偏头痛发作期间的病史和偏头痛症状。越来越多的研究表明,影响VM的主要因素就是基因变异,目前偏头痛的相关基因尚在研究中,具体有多少种相关性基因尚不明确,本文的目的是研读偏头痛相关基因的文献并予以综述。Vestibular migraine(VM)is an acute ves tibular syndrome,which is considered to be one of the m ost common causes of recurrent vertigo.During the onset of vertigo,spontaneous or postural vertigo,visual vertigo,blurred vision and other clinical manifestations may occur.Its main diagnostic basis is the history during the onset of migraine and symptoms of migraine.More and more studies have shown that the main factor affecting VM is gene variation.At present,the genes related to migraine are still under study,and the specific number of related genes is not clear.This paper is intended to study and summarize the literature of migraine related genes.

关 键 词：前庭偏头痛 SCN1A基因 SLC1A3基因 PBMC基因表达谱 早期生长反应基因1 CAV1基因 KCNA1基因 TRPM7基因 CACNA1A基因 ATPlA2基因 

分 类 号：R747.2[医药卫生—神经病学与精神病学]