颅内动脉瘤性蛛网膜下腔出血患者介入术后抑郁的危险因素  

The risk factors of depression on intracranial aneurysmal subarachnoid hemorrhage patients after interventional therapy

作　　者：杨利超 赵中甫 胡国超 刘凯歌 张峰涛 YANG Lichao;ZHAO Zhongfu;HU Guochao(Department of Neurosurgery,Xuchang Central Hospital,Xuchang 461000,China)

机构地区：[1]许昌市中心医院神经外科,许昌461000

出　　处：《国际精神病学杂志》2022年第5期849-852,共4页Journal Of International Psychiatry

摘　　要：目的探讨颅内动脉瘤性蛛网膜下腔出血(aSAH)患者介入术后出现抑郁的危险因素。方法纳入2017年1月~2021年3月104例aSAH患者,均采用介入手术治疗,记录术后住院期间抑郁发生率,设为抑郁组与正常组,比较两组患者美国国立卫生院神经功能缺损评分(NHISS)、家庭经济、文化程度、Hunt&Hess分级、手术时机、年龄、术后睡眠障碍等病历资料。采用单因素及多因素分析确定术后抑郁的危险因素。结果104例aSAH患者介入术后48例发生抑郁;抑郁组与正常组NHISS评分、家庭经济、文化程度、Hunt&Hess分级、手术时机、年龄、术后睡眠障碍、医疗支付方式差异具有统计学意义(P<0.05),两组性别、婚姻情况差异无统计学意义(P>0.05);多因素分析显示,NHISS评分>15分、Hunt&Hess分级Ⅲ级、手术时机>48h、年龄>70岁、术后睡眠障碍、家庭经济情况差、小学及以下文化程度是aSAH介入术后抑郁的危险因素。结论aSAH介入术后早期抑郁发生率较高,受到NHISS评分、家庭经济、文化程度、年龄等因素的影响,应对高危患者重点关注,采取积极措施降低抑郁发生率。Objective To explore the risk factors of depression on intracranial aneurysmal subarachnoid hemorrhage patients after interventional therapy.Methods A total of 104 patients with aSAH from January 2017 to March 2021 were enrolled.All patients were treated with interventional surgery.The incidence of depression within hospitalization after the operation was recorded and set as the depression group and the normal group.The National Institutes of Health Neurological Impairment Score(NHISS),family economy,educational level,Hunt&Hess classification,operation timing,age,postoperative sleep disturbance and other medical records were compared between the two groups of patients.Univariate and multivariate analysis were used to determine the risk factors for postoperative depression.Results 48 patients with aSAH after intervention occurred depression.There were statistically significant differences between the depression group and the normal group inNHISS score,family economy,education level,Hunt&Hess classification,operation timing,age,postoperative sleep disturbance,and medical payment method(P<0.05).There were no significant differences in gender,and marital status between the two groups(P>0.05).Multivariate analysis showed that NHISS score>15 points,Hunt&Hess gradeⅢ,operation timing>48h,age>70 years old,postoperative sleep disturbance Poor family financial situation and primary school and below education level are risk factors for depression after aSAH intervention.Conclusion The incidence of early depression after aSAH intervention is relatively high.It is affected by factors such as NHISS score,family economy,education level,and age.High-risk patients should be paid more attention to and active measures should be taken to reduce the incidence of depression.

关 键 词：颅内动脉瘤性蛛网膜下腔出血 介入术 抑郁 危险因素 

分 类 号：R749.13[医药卫生—神经病学与精神病学]