有机化学综合实验设计--以《可见光诱导的β-羰基砜的合成》为例  

Design of Comprehensive Experiment in Organic Chemistry:Taking Visible-light Induced Synthesis ofβ-Carbonyl Sulfone as an Example

作　　者：朱海波 孟佳 谢宗波[1] ZHU Hai-bo;MENG Jia;XIE Zong-bo(School of Chemistry Biology and Materials Science,East China University of Technology,Nanchang,Jiangxi 330013,China)

机构地区：[1]东华理工大学化学生物与材料科学学院,江西南昌330013

出　　处：《教育教学论坛》2022年第49期78-81,共4页Education And Teaching Forum

基　　金：2021—2022年度东华理工大学教学改革研究课题“创新能力培养视角下《有机化学实验》模块化教学的实践探索”(DHJG-21-45)。

摘　　要：在国内的本科院校中,有机化学教学实验基本上拘泥于传统热反应合成方法,使用强毒性及腐蚀性的化学试剂和溶剂,对环境污染严重。基于可见光催化有机反应具有条件温和、溶剂绿色、操作简单、环保等优点,设计了光催化下芳基亚磺酸钠和2-溴苯乙酮的偶联,从β-羰基砜的合成、分离和结构鉴定几个方面,进行了一次有机化学实验教学改革,取得了比较理想的实验效果。In domestic undergraduate colleges and universities, the organic chemistry teaching experiment is basically confined to the traditional thermal reaction synthesis method, using highly toxic and corrosive chemical reagents and solvents, causing serious environmental pollution. Based on the advantages of visible light catalytic organic reaction such as mild conditions, green solvent, simple operation and environmental protection, we designed the coupling of sodium aryl sulfite and 2-bromoacetophenone. from the synthesis, separation and structure identification of β-carbonyl sulfone, an organic chemistry experiment teaching reform is carried out, and satisfactory experimental results have been achieved.

关 键 词：可见光诱导 有机合成 综合性实验 β-羰基砜 

分 类 号：G642[文化科学—高等教育学]