动脉灌注化疗栓塞术联合腔内支架置入治疗食管癌的临床效果  

Clinical Effect of Arterial Infusion Chemoembolization Combined with Intracavitary Stent Implantation in the Treatment of Esophageal Cancer

作　　者：王秀娟 魏林 张建民 WANG Xiujuan;WEI Lin;ZHANG Jianmin(Department of Intervention,Zhumadian First People’s Hospital,Zhumadian 463000,China)

机构地区：[1]驻马店市第一人民医院介入科,河南驻马店463000

出　　处：《河南医学研究》2022年第23期4334-4338,共5页Henan Medical Research

摘　　要：目的探究动脉灌注化疗栓塞术联合腔内支架置入对食管癌患者的临床治疗效果。方法以驻马店市第一人民医院在2019年3月至2021年10月收治的食管癌患者共68例作为研究样本,将其随机分配为两组,对照组(34例)接受腔内支架置入治疗,联合组(34例)接受动脉灌注化疗栓塞术联合腔内支架置入治疗。对比两组临床治疗效果、术后并发症发生情况及治疗前后吞咽困难分级。结果联合组患者的总有效率高于对照组,差异有统计学意义(P<0.05);联合组骨髓抑制发生率高于对照组,差异有统计学意义(P<0.05);两组患者其他并发症发生率对比,差异无统计学意义(P>0.05);治疗前,两组患者吞咽困难分级主要为3级,差异无统计学意义(P>0.05);治疗后,联合组1级吞咽困难例数多于对照组,差异有统计学意义(P<0.05);其他吞咽困难分级,差异无统计学意义(P>0.05)。结论动脉灌注化疗栓塞术联合腔内支架置入治疗食管癌的临床效果良好,可明显减轻患者的吞咽困难症状,提高生活质量。Objective To explore the clinical therapeutic effect of arterial infusion chemoembolization combined with intracavitary stent implantation on patients with esophageal cancer.Methods A total of 68 patients with esophageal cancer treated in Zhumadian First People’s Hospital from March 2019 to October 2021 were set as the study samples and randomly divided them into two groups.The control group(34 cases)was treated with endovascular stent implantation,and the combined group(34 cases)was treated with arterial perfusion chemoembolization combined with endovascular stent implantation.The clinical therapeutic effect,postoperative complications and the classification of dysphagia before and after treatment was compared of patients in the two groups.Results The total effective rate of patients in the combined group was higher than that of the control group,and the difference was statistically significant(P<0.05).The incidence of bone marrow suppression in the combined group was higher than that in the control group,the difference was statistically significant(P<0.05).There was no statistical significant difference in the incidence of other complications of patients in both groups(P>0.05).Before treatment,the grade of dysphagia of patients in both groups was mainly grade 3,and the difference was not statistically significant(P>0.05).After treatment,the number of patients with grade 1 dysphagia in the combined group was more than that in the control group,and the difference was statistically significant(P<0.05).There was no statistical significant difference in other dysphagia grades(P>0.05).Conclusion Arterial infusion chemoembolization combined with intracavitary stent implantation is effective in the treatment of esophageal cancer,which can significantly reduce the symptoms of dysphagia and improve the quality of life of patients.

关 键 词：食管癌 动脉灌注化疗栓塞术 腔内支架置入 吞咽困难 

分 类 号：R735.1[医药卫生—肿瘤]