选择性激光小梁成形术联合激光周边虹膜切开术治疗色素性青光眼的疗效探讨  

Efficacy of selective laser trabeculoplasty combined with laser peripheral iridotomy on pigmentary glaucoma

作　　者：肖玥言 郗平 高博[1] 王嘉南 耿云云 郑敏 XIAO Yue-yan;XI Ping;GAO Bo(Department of Ophthalmology,Airport Hospital of Shunyi District,Beijing 101318,China)

机构地区：[1]北京市顺义区空港医院眼科,101318

出　　处：《中国实用医药》2022年第24期72-76,共5页China Practical Medicine

摘　　要：目的研究选择性激光小梁成形术(SLT)联合激光周边虹膜切开术(LPI)治疗色素性青光眼的临床疗效。方法10例(20眼)色素性青光眼患者均进行SLT联合LPI治疗。比较患者治疗前后眼压、视力及中央区视网膜厚度,观察患者治疗效果及视网膜神经纤维层损害情况及视野情况。结果患者SLT治疗前右眼和左眼眼压与LPI治疗前比较,差异无统计学意义(P>0.05);SLT治疗后1 d、1周及1、3、6个月右眼和左眼眼压均低于SLT治疗前,差异具有统计学意义(P<0.05);SLT治疗后6个月右眼和左眼眼压高于治疗后3个月,差异具有统计学意义(P<0.05)。患者治疗显效6例(60%),有效4例(40%),无效0例,治疗总有效率为100%。治疗前,右眼视力为(0.98±0.06)、中央区视网膜厚度为(262.10±10.75)μm,左眼视力为(0.96±0.07)、中央区视网膜厚度为(265.90±7.23)μm;治疗后,右眼视力为(0.96±0.08)、中央区视网膜厚度为(267.60±9.61)μm,左眼视力为(0.96±0.08)、中央区视网膜厚度为(269.50±8.00)μm。治疗前后,两眼视力、中央区视网膜厚度比较,差异无统计学意义(P>0.05)。10例患者的小梁网色素分级未加重,视网膜神经纤维层损害及视野均未进展。结论SLT联合LPI可以有效控制色素性青光眼的眼压和色素播散沉积,患者视力、视网膜厚度及视野均保持稳定。Objective To study the clinical efficacy of selective laser trabeculoplasty(SLT)combined with laser peripheral iridotomy(LPI)on pigmentary glaucoma.Methods 10 patients(20 eyes)with pigmentary glaucoma were treated with SLT combined with LPI.The intraocular pressure,visual acuity and central retinal thickness before and after treatment were compared,and the therapeutic effect,retinal nerve fiber layer damage and visual field were observed.Results There was no statistically significant difference in the intraocular pressure of the right eye and left eye before SLT treatment and before LPI treatment(P>0.05).The intraocular pressure of the right eye and left eye at 1 d,1 week,and 1,3,and 6 months after SLT treatment were lower than those before SLT treatment,and the differences were all statistically significant(P<0.05).At 6 months after SLT treatment,the intraocular pressure of the right eye and left eye was higher than that at 3 months after treatment,and the difference was statistically significant(P<0.05).6 cases(60%)were markedly effective,4 cases(40%)were effective,and 0 cases were ineffective,and the total effective rate was 100%.Before treatment,the visual acuity of the right eye was(0.98±0.06),the central retinal thickness was(262.10±10.75)μm;the visual acuity of the left eye was(0.96±0.07),and the central retinal thickness was(265.90±7.23)μm.After treatment,the visual acuity of the right eye was(0.96±0.08),the central retinal thickness was(267.60±9.61)μm;the visual acuity of the left eye was(0.96±0.08),and the central retinal thickness was(269.50±8.00)μm.Before and after treatment,there was no statistically significant difference in visual acuity and central retinal thickness between the right eye and the left eye(P>0.05).The trabecular meshwork pigment grading did not worsen in 10 patients,and the retinal nerve fiber layer damage and visual field did not progress.Conclusion SLT combined with LPI can effectively control the intraocular pressure and pigment dissemination deposition in pigmented g

关 键 词：选择性激光小梁成形术 激光周边虹膜切开术 色素性青光眼 色素播散综合征 

分 类 号：R779.6[医药卫生—眼科]