雌激素与女性卒中血栓形成机制研究进展  

Research progress of estrogen on thrombosis in women with stroke

作　　者：宋庆丽 方天颖 张琳 Song Qingli;Fang Tianying;Zhang Lin(the Second Clinical Medical College of Shaanxi University of Chinese Medicine,Xianyang,Shaanxi 712046,China)

机构地区：[1]陕西中医药大学第二临床医学院,咸阳712046 [2]西安市人民医院(西安市第四医院)神经内科

出　　处：《中国脑血管病杂志》2022年第12期861-866,共6页Chinese Journal of Cerebrovascular Diseases

基　　金：西安市人民医院(西安市第四医院)科研孵化基金项目(市人医发[2020]105号);西安市2022年博士后创新基地资助项目(2022BSHCX08)。

摘　　要：女性卒中有其独特的病因和危险因素。在自身免疫性疾病和血栓性疾病筛查中,女性卒中患者的异常率较高。雌激素可通过血管组织、炎性反应、血栓形成等多种方式引起卒中,但其具体机制尚不清楚,有待进一步探讨。该文从雌激素影响血管组织、促进血管炎性反应、引起血栓形成等方面探讨女性卒中的独特发病机制。Female stroke has unique etiology and risk factors.In the screening of autoimmune diseases and thrombotic diseases,women have a higher rate of stroke related abnormalities.It is found that estrogen can cause stroke by inducing vascular tissue damage,activating inflammatory response and promoting thrombosis,but its specific mechanism is not clear and needs to be further discussed.This paper discussed the unique pathogenesis of female stroke from the aspects of estrogen affecting vascular tissue,promoting vasculitis and causing thrombosis.

关 键 词：女性 卒中 受体 雌激素 血栓形成 综述 

分 类 号：R743.3[医药卫生—神经病学与精神病学]