结直肠侧向发育型肿瘤伴结直肠息肉的相关因素分析  

Analysis on correlative factors for colorectal laterally spreading tumor with colorectal polyps

作　　者：张曦予 李未华[1] 徐泉 黄华[1] 赵公芳[1] ZHANG Xi-yu;LI Wei-hua;XU Quan;HUANG Hua;ZHAO Gong-fang(Department of Gastroenterology,The Second Affiliated Hospital of Kunming Medical Univerity,650101;Department of gastroenterology,Hanzhong People′s Hospital,723000)

机构地区：[1]昆明医科大学第二附属医院消化内科,650101 [2]陕西省汉中市人民医院消化内科,723000

出　　处：《现代消化及介入诊疗》2022年第8期966-969,共4页Modern Interventional Diagnosis and Treatment in Gastroenterology

基　　金：云南省“万人计划”名医人才专项(YNWR-MY-2019-074);昆明医科大学第二附属医院院内科技计划项目(2021yk008)。

摘　　要：背景结直肠侧向发育型肿瘤(LST)和结直肠息肉均被认为是结直肠癌(CRC)的癌前病变,且LST常常伴随结直肠息肉发生发展。目的探索LST伴结直肠息肉的相关因素。方法对2016年1月至2021年12月昆明医科大学第二附属医院结肠镜检查病理诊断为LST的173例住院患者进行回顾性分析。其中LST伴结直肠息肉组95例,LST不伴结直肠息肉组78例。结果LST伴结直肠息肉组的年龄、男性、有吸烟史、饮酒史、LST<3 cm、LST位于近端结肠、WBC计数、NEUT计数水平高于LST不伴结直肠息肉组,HDL-C水平低于LST不伴结直肠息肉组,均具有统计学差异(P<0.05);两组间在首发症状、民族、LST-G、既往有息肉病史、BMI、UA、TC、TG、LDL-C上差异无统计学差异(P>0.05)。二元Logistic回归分析显示:年龄、LST直径<3 cm是LST伴发结直肠息肉的独立危险因素(P<0.05)。结论性别、年龄、吸烟史、饮酒史、LST大小、LST部位、WBC计数、NEUT计数、HDL-C是LST伴结直肠息肉的影响因素。年龄、LST直径<3 cm是LST伴发结直肠息肉的独立危险因素。Objective Laterally spreading tumors(LST)and colorectal polyps are considered to be precancerous lesions of colorectal cancer,but LST is often accompanied by the occurrence and development of colorectal polyps.Aims To explore the correlative factors of colorectal LST with colorectal polyps.Methods A total of 173 inpatients with LST diagnosed pathologically by colonoscopy from January 2016 to December 2021 in the Second Affiliated Hospital of Kunming Medical University were retrospectively analyzed.Among them,95 cases were LST with colorectal polyps and 78 cases were LST without colorectal polyps.Results The age,male,smoking history,drinking history,LST<3 cm,LST located in the proximal colon,WBC count,NEUT count levels of LST with colorectal polyps group were higher than those of control group and HDL-C were lower than those of control group,and the differences were statistically significant(P<0.05).There were no significant differences in initial symptom,Han nationality,LST-G,colorectal polyps history,BMI、UA、TC、TG、LDL-C between LST with colorectal polyps group and control group(P>0.05).Multivariate logistic regression analysis was used to analyze the risk factors of colorectal adenomatous polyps.The results were as follows:age,LST diameter<3 cm were independent risk factors of LST with colorectal polyps(P<0.05).Conclusion Gender,age,smoking history,drinking history,LST size,LST location,WBC count,NEUT count,and HDL-C were the influencing factors of LST with colorectal polyps.Age and LST diameter<3 cm were independent risk factors for LST complicated with colorectal polyps.

关 键 词：结直肠侧向发育型肿瘤 结直肠息肉 危险因素 

分 类 号：R574[医药卫生—消化系统]