营养干预对结直肠癌术后辅助化疗患者营养状况及生活质量的影响  

Effects of Nutritional Intervention on Nutritional Status and Quality of Life of Patients with Colorectal Cancer Treated with Postoperative Adjuvant Chemotherapy

作　　者：倪婷[1] 高红玉 赵丹[1] 王海存[2] NI Ting;GAO Hongyu;ZHAO Dan;WANG Haicun(Department of Nutrition,The Third People's Hospital of Zhengzhou(Cancer Hospital of Zhengzhou),Zhengzhou 450000,China;Department of Digestive Oncology,The Third People's Hospital of Zhengzhou(Cancer Hospital of Zhengzhou),Zhengzhou 450000,China)

机构地区：[1]郑州市第三人民医院(郑州市肿瘤医院)营养科,郑州450000 [2]郑州市第三人民医院(郑州市肿瘤医院)消化肿瘤科,郑州450000

出　　处：《肿瘤防治研究》2022年第12期1286-1290,共5页Cancer Research on Prevention and Treatment

基　　金：河南省医学科技攻关项目(LHGJ20200720)。

摘　　要：目的探讨营养干预对结直肠癌术后辅助化疗患者营养状况和生活质量的影响。方法选取56例结直肠癌术后辅助化疗患者,据其营养干预情况分为对照组(36例)和营养干预组(20例),比较两组患者手术4周后血液指标、PG-SGA评分和生活质量评价SF-36量表评分差异。结果营养干预组和对照组患者入院时的PG-SGA评分比较差异无统计学意义(t=-0.347,P=0.730),而4周后的PG-SGA评分差异有统计学意义(t=-2.708,P=0.009)。4周后,两组患者血清前白蛋白、白蛋白、血红蛋白比较差异无统计学意义(P>0.05);生活质量评分除了情感职能这一指标差异无统计学意义(P=0.083),其他指标差异均有统计学意义(P<0.05),且营养干预组得分均高于对照组。结论营养干预能有效改善结直肠癌术后辅助化疗患者的营养状况和生活质量。Objective To explore the effects of nutritional intervention on the quality of life and nutritional status of patients with colorectal cancer treated with postoperative adjuvant chemotherapy.Methods Fiftysix patients with colorectal cancer subjected to postoperative chemotherapy were selected.They were divided into nutritional intervention group(n=20)and control group(n=36).Blood test indices,PG-SGA scores,and 36-Item Short Form Health Survey scores were compared 4 weeks after the surgery.Results No significant difference in PG-SGA score was found between the nutritional group and the control group at admission(t=-0.347,P=0.730),but statistically significant difference was detected after 4 weeks(t=-2.708,P=0.009).At 4 weeks after the surgery,the serum levels of prealbumin,albumin,and hemoglobin were not significantly different between the two groups(P>0.05).Other indices of quality of life assessment(P<0.05),except for the index of emotional function(P=0.083),were significantly different between the two groups,and the scores of the nutritional intervention group were higher than those of the control group.Conclusion Nutritional intervention can effectively improve the nutritional status and quality of life of patients with colorectal cancer treated with postoperative adjuvant chemotherapy.

关 键 词：营养干预 生活质量 结直肠癌 辅助化疗 

分 类 号：R735.3[医药卫生—肿瘤]