单细胞转录组测序在鼻咽癌免疫微环境中的研究进展  

Research Progress of Single-cell Transcriptome Sequencing in Immune Microenvironment of Nasopharyngeal Carcinoma

作　　者：应敏 刘金坤[2] YING Min;LIU Jinkun(Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment,Chongqing University Cancer Hospital,Chongqing 400030,China;Basic Research Laboratory of Traditional Chinese Medicine,Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China)

机构地区：[1]重庆大学附属肿瘤医院肿瘤转移与个体化诊治转化研究重庆市重点实验室,重庆400030 [2]重庆市中医院中医药基础研究室,重庆400021

出　　处：《肿瘤防治研究》2022年第12期1291-1295,共5页Cancer Research on Prevention and Treatment

基　　金：国家自然科学基金(81904042);重庆市自然科学基金(cstc2021jcyj-msxmX0852);重庆中医院人才项目(CQSZYY1146)。

摘　　要：分析近年来鼻咽癌单细胞转录组测序的研究进展,对鼻咽癌免疫微环境进行剖析,总结髓系细胞、T细胞、B细胞、NK细胞等免疫细胞和成纤维细胞在鼻咽癌组织中的作用机制,为鼻咽癌的诊断、治疗和预后预测提供参考。We analyze the recent research progress of single-cell transcriptome sequencing of nasopharyngeal carcinoma(NPC),dissect its tumor immune microenvironment,and focus on the role of myeloid cells,T cells,B cells,NK cells,and fibroblasts in the mechanism of action in NPC tissues to provide reference for the diagnosis,treatment,and prognosis prediction of NPC.

关 键 词：鼻咽癌 单细胞转录组测序 肿瘤免疫微环境 

分 类 号：R739.63[医药卫生—肿瘤]