64排螺旋CT灌注成像多参数联合用于肺癌纵隔淋巴结转移的临床价值  

Clinical Value of 64-slice Spiral CT Perfusion Imaging on Multiple Parameters in the Diagnosis of Mediastinal Lymph Node Metastasis of Lung Cancer

作　　者：江新华 JIANG Xinhua(Nanchang First Hospital,Nanchang 330008,China)

机构地区：[1]南昌市第一医院,江西南昌330008

出　　处：《中国医学创新》2022年第36期147-150,共4页Medical Innovation of China

基　　金：江西省卫生健康委员会科技计划项目(202140002)。

摘　　要：目的:分析64排螺旋CT灌注成像多参数联合用于肺癌纵隔淋巴结转移诊断的临床价值。方法:选择南昌市第一医院2020年1月-2022年1月收治的106例肺癌患者。在患者接受手术治疗前,进行CT平扫、增强扫描及灌注扫描检查,对CT扫描结果进行统计。以术后淋巴结病理诊断结果为诊断金标准,对CT检查相关参数诊断肺癌纵隔淋巴结转移价值进行分析。结果:本研究106例受试者,术后纵隔淋巴结病理诊断结果显示65例患者出现纵隔淋巴结转移,纵隔淋巴结转移率为61.32%。转移组与非转移组肺动脉血流量(PAF)比较,差异无统计学意义(P>0.05);转移组支气管动脉血流量(BAF)高于非转移组,灌注指数(PI)低于非转移组,差异均有统计学意义(P<0.05)。PAF诊断肺癌纵隔淋巴结转移敏感度为63.40%、特异度为41.50%;BAF诊断肺癌纵隔淋巴结转移敏感度为75.38%、特异度为87.80%;PI诊断肺癌纵隔淋巴结转移敏感度为74.82%、特异度为58.54%。结论:针对肺癌患者,应用64排螺旋CT灌注成像诊断是否发生纵隔淋巴结转移具有较高的可行性,可为临床治疗肺癌提供重要的参考依据。Objective:To analyze the clinical value of 64-slice spiral CT perfusion imaging on multiple parameters in the diagnosis of mediastinal lymph node metastasis of lung cancer.Method:A total of 106 patients with lung cancer admitted to Nanchang First Hospital from January 2020 to January 2022 were selected.Before the patients received surgical treatment,CT plain scan,enhanced scan and perfusion scan were performed,and the CT scan results were counted.The value of CT parameters in the diagnosis of mediastinal lymph node metastasis of lung cancer were analyzed with postoperative lymph node diagnosis as the gold standard.Result:Among 106 subjects in this study,postoperative pathological diagnosis of mediastinal lymph nodes showed that 65 patients had mediastinal lymph node metastasis,and the mediastinal lymph node metastasis rate was 61.32%.There was no significant difference in pulmonary artery blood flow(PAF) between metastasis group and non-metastasis group(P>0.05).The bronchial arterial blood flow(BAF) in the metastasis group was higher than that in the non-metastasis group,and the perfusion index(PI) in the metastasis group was lower than that in the non-metastasis group,the differences were statistically significant(P<0.05).The sensitivity and specificity of PAF in the diagnosis of mediastinal lymph node metastasis of lung cancer were 63.40% and 41.50%.The sensitivity and specificity of BAF in the diagnosis of mediastinal lymph node metastasis of lung cancer were 75.38% and 87.80%.The sensitivity and specificity of PI in the diagnosis of mediastinal lymph node metastasis of lung cancer were 74.82% and 58.54%.Conclusion:For lung cancer patients,the application of 64-slice spiral CT perfusion imaging in the diagnosis of mediastinal lymph node metastasis has high feasibility,and can provide an important reference for the clinical treatment of lung cancer.

关 键 词：64排螺旋CT灌注成像 肺癌 纵隔淋巴结转移 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]