青花椒果壳渣生物发酵产物滤液抗衰老功效探究  

Anti-aging Effect of Filtrate from Biological Fermentation Product of Shell Residue of Zanthoxylum schinifolium

作　　者：束成杰 张锋伦 赵孔发 李卓航 冯志营 傅雷 郑丹[4] 张卫明[1,2] Shu Chengjie;Zhang Fenglun;Zhao Kongfa;Li Zhuohang;Feng Zhiying;Fu Lei;Zheng Dan;Zhang Weiming(Nanjing Institute for Comprehensive Utilization of Wild Plants,Nanjing 211111,China;Jiangsu Natural Perfume Engineering Technology Center,Nanjing 211111,China;Zhaotong Dacheng Agricultural Development Co.,Ltd.,Zhaotong 6571004,China;Taizhou College of Nanjing Normal University,Taizhou 225300,China)

机构地区：[1]南京野生植物综合利用研究所,江苏南京211111 [2]江苏省天然香料工程技术中心,江苏南京211111 [3]昭通市大成农业开发有限责任公司,云南昭通6571004 [4]南京师范大学泰州学院,江苏泰州225300

出　　处：《中国野生植物资源》2022年第12期30-34,共5页Chinese Wild Plant Resources

基　　金：云南省张卫明专家工作站、云南省“万人计划”产业技术领军人培养计划项目支持;云南省科技入滇项目——昭通天麻“两菌”技术体系与马铃薯、花椒产业提质增效(202003AD150005)。

摘　　要：目的:青花椒果壳渣生物发酵提取,得到青花椒果壳发酵产物滤液。方法:基于模式动物秀丽线虫对上述发酵滤液进行生物活性探究。结果:1%、2%、4%的发酵产物滤液均能够延长秀丽线虫寿命、提高其运动行为能力和吞咽频率,降低肠道氧自由基水平。同时,青花椒果壳渣发酵产物滤液还能够缩短秀丽线虫的排泄周期,提高其代谢能力。此外,秀丽线虫在35℃热激6 h条件下,4%浓度处理的线虫也能显著提高热应激能力。结论:青花椒果壳渣发酵产物滤液具有延缓秀丽线虫衰老,延长寿命的作用。Purpose:The shell of Zanthoxylum schinifolium were extracted by biological fermentation,and the filtrate of the fermentation product for Z.schinifolium were obtained.Methods:The biological activities of the above fermentation filtrates were investigated based on the model animal C.elegans.Results:1%,2%and 4%filtrates of fermentation could extend the lifespan of C.elegans,improve the locomotion ability and pumping frequency,and reduce the express of intestinal ROS.In addition,the filtrate of fermentation from the shell residue for Z.schinifolium could shorten the defecation cycle of C.elegans and improve its metabolic capacity.What’s more,4%fermentation also significantly increased the heat stress ability of C.elegans treated with heat shock at 35℃for 6 h.Conclusions:The filtrate of fermentation from Z.schinifolium can prolong the senescence and prolong the life of C.elegans.

关 键 词：青花椒果 生物发酵 秀丽线虫 抗衰老 体内 

分 类 号：Q33[生物学—遗传学]