2017年山西省肿瘤登记地区上消化道癌的流行现状及2013-2017年发病与死亡趋势分析  

Incidence and Mortality of Upper Gastrointestinal Cancer in Shanxi Cancer Registration Areas in 2017 and the Trends from 2013 to 2017

作　　者：武婧 崔王飞 曹凌[2] 郭雪蓉[2] 王昕琛[2] 张瑞锋[2] 张永贞[1,2] WU Jing;CUIWang-fei;CAO Ling;GUO Xue-rong;WANG Xin-chen;ZHANG Rui-feng;ZHANG Yong-zhen(School of Public Health,Shanxi Medical University,Taiyuan 030001,China;Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital,Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University,Taiyuan 030013,China)

机构地区：[1]山西医科大学公共卫生学院,山西太原030001 [2]山西省肿瘤医院/中国医学科学院肿瘤医院山西医院/山西医科大学附属肿瘤医院,山西太原030013

出　　处：《中国肿瘤》2022年第11期869-877,共9页China Cancer

基　　金：大气污染成因与治理攻关项目(DQGG0404)。

摘　　要：[目的]分析2017年山西省肿瘤登记地区的上消化道癌流行现状及2013-2017年的发病率和死亡率趋势变化。[方法]整理2013-2017年山西省肿瘤登记地区上消化道癌发病、死亡数据及人口资料。根据2017年符合质量审核标准的数据,计算上消化道癌的粗发病(死亡)率、中国人口标准化率(简称中标率)、世界人口标准化率(简称世标率)、累积发病(死亡)率(0~74岁)以及年龄别发病(死亡)率,标准人口采用全国2000年普查标准人口构成和Segi’s世界标准人口构成。利用Joinpoint 4.9.1.0软件,计算2013-2017年山西省肿瘤登记地区上消化道癌中标发病(死亡)率的年度变化百分比(annual percentage change,APC),了解其时间变化趋势特征。[结果] 2017年山西省肿瘤登记地区共有上消化道癌新发病例3 299例,粗发病率为67.76/10万,中标率为46.38/10万,世标率为47.48/10万,累积发病率(0~74岁)为6.21%;上消化道癌死亡病例2 229例,粗死亡率为45.78/10万,中标率为30.95/10万,世标率为31.74/10万,累积死亡率(0~74岁)为3.75%。2017年山西省肿瘤登记地区上消化道癌的发病率和死亡率分别从40~岁和45~岁年龄组开始随着年龄的增加而增长,且呈现出了农村地区高于城市地区、男性高于女性的特点。2013-2017年,山西省肿瘤登记地区上消化道癌中标发病率整体呈下降趋势(APC=-4.08%),城市地区和农村地区上消化道癌的中标发病率均以不同幅度下降(APC为-3.01%和-5.55%),但趋势变化无统计学意义(P>0.05);山西省肿瘤登记地区上消化道癌中标死亡率整体呈下降趋势(APC=-2.08%),城市地区呈小幅上升趋势(APC=2.11%),农村地区呈下降趋势(APC=-4.55%),但趋势变化无统计学意义(P>0.05)。[结论 ] 2013-2017年山西省肿瘤登记地区上消化道癌的中标发病率和中标死亡率略有下降,但仍处于较高水平。为了提高上消化道癌的整体防治水平,应重点关注男性人群、农村地区[Purpose] To analyze the incidence and mortality of upper gastrointestinal cancer in Shanxi cancer registration areas in 2017 and the epidemiological trends from 2013 to 2017.[Methods] The incidence, mortality and population data of upper gastrointestinal cancer in Shanxi cancer registration areas from 2013 to 2017 were collected and sorted. The crude incidence/mortality rates, age-standardized incidence/mortality rates by Chinese standard population(ASR China), age-standardized incidence/mortality rates by world standard population(ASR world), the cumulative incidence/mortality rates(0~74 years old), and age-specific incidence/mortality rates were calculated from data that met the check standards. Chinese census standard population composition in 2000 and Segi’s world standard population composition were used to calculate the age-standardized rates. The Joinpoint 4.9.1.0 software was used to calculate the annual percentage change(APC) of ASR China of incidence/mortality of upper gastrointestinal cancer in Shanxi cancer registration areas from 2013 to 2017, so as to understand the temporal changing trend characteristics of upper gastrointestinal cancer. [Results] In 2017, there were 3 299 new cases of upper gastrointestinal cancer in the cancer registration areas of Shanxi Province, the crude incidence rate was 67.76/10^(5), the ASR China was 46.38/10^(5), the ASR world was 47.48/10^(5),and the cumulative incidence rate(0~74 years old) was 6.21%. There were 2 229 deaths of upper gastrointestinal cancer, the crude mortality rate was 45.78/10^(5), the ASR China was 30.95/10^(5), the ASR world was 31.74/10^(5), and the cumulative mortality rate(0~74 years old) was 3.75%. In 2017,the incidence and mortality rate of upper gastrointestinal cancer in the cancer registration areas increased rapidly with age from the 40 years old and the 45 years old, respectively, and the rates were higher in rural areas than those in urban areas and higher in male than those in female. From 2013 to 2017, the ASR China of incidence of

关 键 词：上消化道癌 发病 死亡 流行特征 趋势 山西 

分 类 号：R73-31[医药卫生—肿瘤] R735[医药卫生—临床医学]