家禽营养表观遗传学研究进展  

Advances in Poultry Nutrition Epigenetics

作　　者：曾文惠 曾庆节 殷超 黄建珍[1] ZENG Wenhui;ZENG Qingjie;YIN Chao;HUANG Jianzhen(College of Animal Science and Technology,Jiangxi Agricultural University,Nanchang 330045,China)

机构地区：[1]江西农业大学动物科学技术学院,南昌330045

出　　处：《动物营养学报》2022年第12期7546-7554,共9页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金项目(31960690,32160822)。

摘　　要：表观遗传是在不改变DNA碱基序列的前提下,引起基因表达改变的一种可遗传现象。营养表观遗传学作为表观遗传学的一个重要分支,主要通过研究营养素对染色质修饰的影响,进而从分子水平解释早期营养及其他环境因素的变化对后期健康的影响机制。目前,表观遗传修饰和营养调控的研究已成为营养学领域新的研究热点。多项研究表明,营养素可通过对表观遗传的调控改善家禽生产性能,并提高家禽生产力。本文主要论述了表观遗传调控与家禽生产性能的关系,并从深层次阐明各营养素通过影响表观遗传修饰从而改善家禽生长发育及生产性能的具体分子机制。Epigenetic is a heritable variation of gene expression alterations without changing the DNA base sequence.Nutritional epigenetics,as an important branch of epigenetics,mainly studies the effects of nutrients on chromatin modification,and then explains the molecular mechanism of early nutritional and other environmental factors affecting later health in animals.At present,the study of epigenetic modification and nutritional regulation has become a new research hotspot in the field of nutritional science.Several studies have shown that nutrition can improve poultry performance and increase poultry productivity through epigenetic regulation.This paper mainly discussed the relationship between epigenetic regulation and poultry production performance,and in-depth elucidated the specific molecular mechanism of each nutrient through affecting epigenetic modification to improve poultry growth,development and performance.

关 键 词：营养 家禽 营养表观遗传 DNA甲基化 组蛋白修饰 非编码RNA调控 

分 类 号：S83[农业科学—畜牧学]