疑似儿童神经母细胞瘤识别及转诊指南  

Guideline for identification and referral of suspected paediatric neuroblastoma

作　　者：马晓莉[1] 彭晓霞[2] 段超[1] 王焕民[3] 苏雁[1] 刘雅莉 何乐健[4] 王晓曼[5] 于彤[6] 周宇晨[1] 蒋持怡 朱帅 MA Xiaoli;PENG Xiaoxia;DUAN Chao;WANG Huanmin;SU Yan;LIU Yali;HE Lejian;WANG Xiaoman;YU Tong;ZHOU Yuchen;JIANG Chiyi;ZHU Shuai(Medical Oncology Department,Pediatric Oncology Center,Beijing Children’s Hospital,Capital Medical University,National Center for Children’t Health,Beijing Key Laboratory of Pediatric Hematology Oncology,Key Laboratory of Major Diseases in Children,Ministry of Education,Beijing 100045,P.R.China;Center for Clinical Epidemiology and Evidence-Based Medicine,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,P.R.China;Surgical Oncology Department,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,P.R.China;Pathology Department,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,P.R.China;Ultrasonography Department,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,P.R.China;Medical Imaging Department,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,P.R.China)

机构地区：[1]国家儿童医学中心,首都医科大学附属北京儿童医院,儿童肿瘤中心肿瘤内科,北京市儿童血液肿瘤重点实验室,儿科重大疾病研究教育部重点实验室,北京100045 [2]国家儿童医学中心,首都医科大学附属北京儿童医院临床流行病与循证医学中心,北京100045 [3]国家儿童医学中心,首都医科大学附属北京儿童医院肿瘤外科,北京100045 [4]国家儿童医学中心,首都医科大学附属北京儿童医院病理科,北京100045 [5]国家儿童医学中心,首都医科大学附属北京儿童医院超声科,北京100045 [6]国家儿童医学中心,首都医科大学附属北京儿童医院影像科,北京100045

出　　处：《中国循证医学杂志》2022年第11期1241-1248,共8页Chinese Journal of Evidence-based Medicine

摘　　要：神经母细胞瘤(neuroblastoma,NB)是儿童最常见的颅外实体恶性肿瘤。但NB起病隐匿,临床表现多样且不具有特异性,从而导致NB诊断和治疗延迟。为做好NB患儿的早期识别,本指南按照规范的临床指南制订流程,联合多学科专家,基于现有证据及临床实践,制订符合我国国情的NB早期识别和转诊指南。Neuroblastoma(NB)is the most common extracranial solid malignant tumor in children.NB has various clinical manifestations,many of which are not specific,which ultimately lead to the delayed diagnosis of the tumor.In order to provide guidance for the identification of paediatric NB,the guideline for the identification and referral of suspected paediatric neuroblastoma is formulated and complied using a standard formulation process,and has received input from multidisciplinary experts,based on existing evidence,clinical practices and China’s national conditions.

关 键 词：指南 神经母细胞瘤 筛查 转诊 

分 类 号：R739.4[医药卫生—肿瘤]